Diffuse brain oedema in idiopathic intracranial hypertension: a quantitative magnetic resonance imaging study

被引:35
作者
Bastin, ME [1 ]
Sinha, S [1 ]
Farrall, AJ [1 ]
Wardlaw, JM [1 ]
Whittle, IR [1 ]
机构
[1] Univ Edinburgh, Edinburgh, Midlothian, Scotland
关键词
D O I
10.1136/jnnp.74.12.1693
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: To investigate the hypothesis that idiopathic intracranial hypertension is associated with diffuse brain oedema, using quantitative magnetic resonance imaging. Methods: Values for the mean diffusivity of water (<D>) and the proton longitudinal relaxation time (T1) were measured for various brain regions in 10 patients with idiopathic intracranial hypertension and 10 age, sex, and weight matched controls. Results: No significant differences in <D> and T1 values were found between patient and control groups in any of the brain regions investigated. Conclusions: The results suggest that idiopathic intracranial hypertension is not associated with abnormalities of convective transependymal water flow leading to diffuse brain oedema.
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页码:1693 / 1696
页数:4
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