Genetic Regulation of Pre-Pubertal Development of Body Mass Index: A Longitudinal Study of Japanese Twin Boys and Girls

被引：12
作者：
Silventoinen, Karri [1 ,2 ]
Kaprio, Jaakko [1 ,3 ,4 ]
Yokoyama, Yoshie [5 ]
机构：
[1] Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland
[2] Univ Helsinki, Populat Res Unit, Dept Social Res, FIN-00014 Helsinki, Finland
[3] Natl Inst Hlth & Welf, Dept Mental Hlth, Helsinki, Finland
[4] Inst Mol Med FIMM, Helsinki, Finland
[5] Osaka City Univ, Dept Community Hlth Nursing, Osaka 558, Japan
来源：
BEHAVIOR GENETICS | 2011年 / 41卷 / 02期
关键词：
BMI; Children; Genetics; Twins; Asian populations; NATIONAL NUTRITION SURVEY; ENVIRONMENTAL-INFLUENCES; BIRTH-WEIGHT; CHILDHOOD OVERWEIGHT; ADOLESCENT TWINS; SEX-DIFFERENCES; YOUNG TWINS; 8; COUNTRIES; OBESITY; HEIGHT;
D O I：
10.1007/s10519-010-9380-y
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the major proportion (52-74%) of the variation of BMI from 1 to 11 years of age. Environmental factors common to both co-twins also showed some effect (7-28%), but at most ages this was not statistically significant. Strong genetic tracking was found for BMI from 1 to 11 years of age, but there was also evidence for a persistent effect of common environmental factors. Our results suggest that the genetic architecture of BMI development in the Japanese population is generally similar to that found in previous twin studies in Caucasian populations.
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页码：234 / 241
页数：8
相关论文
共 34 条
[1]  
[Anonymous], MULTIPLE PREGNANCY
[2]   Being big or growing fast: systematic review of size and growth in infancy and later obesity [J].
Baird, J ;
Fisher, D ;
Lucas, P ;
Kleijnen, J ;
Roberts, H ;
Law, C .
BMJ-BRITISH MEDICAL JOURNAL, 2005, 331 (7522) :929-931
[3]   THE GENETIC-ANALYSIS OF REPEATED MEASURES .1. SIMPLEX MODELS [J].
BOOMSMA, DI ;
MOLENAAR, PCM .
BEHAVIOR GENETICS, 1987, 17 (02) :111-123
[4]   Sex differences in genetic variation in weight: A longitudinal study of body mass index in adolescent twins [J].
Cornes, Belinda K. ;
Zhu, Gu ;
Martin, Nicholas G. .
BEHAVIOR GENETICS, 2007, 37 (05) :648-660
[5]   Changes in body mass index by birth cohort in Japanese adults: results from the National Nutrition Survey of Japan 1956-2005 [J].
Funatogawa, Ikuko ;
Funatogawa, Takashi ;
Nakao, Mutsuhiro ;
Karita, Kanae ;
Yano, Eiji .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2009, 38 (01) :83-92
[6]   Increasing Heritability of BMI and Stronger Associations With the FTO Gene Over Childhood [J].
Haworth, Claire M. A. ;
Carnell, Susan ;
Meaburn, Emma L. ;
Davis, Oliver S. P. ;
Plomin, Robert ;
Wardle, Jane .
OBESITY, 2008, 16 (12) :2663-2668
[7]   Genetic influences on the difference in variability of height, weight and body mass index between Caucasian and East Asian adolescent twins [J].
Hur, Y-M ;
Kaprio, J. ;
Iacono, W. G. ;
Boomsma, D. I. ;
McGgue, M. ;
Silventoinen, K. ;
Martin, N. G. ;
Luciano, M. ;
Visscher, P. M. ;
Rose, R. J. ;
He, M. ;
Ando, J. ;
Ooki, S. ;
Nonaka, K. ;
Lin, C. C. H. ;
Lajunen, H. R. ;
Cornes, B. K. ;
Bartels, M. ;
van Beijsterveldt, C. E. M. ;
Cherny, S. S. ;
Mitchell, K. .
INTERNATIONAL JOURNAL OF OBESITY, 2008, 32 (10) :1455-1467
[8]  
Hur YM, 2005, TWIN RES HUM GENET, V8, P638, DOI 10.1375/183242705774860169
[9]   Effects of chorion type on genetic and environmental influences on height, weight, and body mass index in South Korean young twins [J].
Hur, Yoon-Mi ;
Shin, Jung-Sik .
TWIN RESEARCH AND HUMAN GENETICS, 2008, 11 (01) :63-69
[10]   A comparative study of zygotic twinning and triplet rates in eight countries, 1972-1999 [J].
Imaizumi, Y .
JOURNAL OF BIOSOCIAL SCIENCE, 2003, 35 (02) :287-302
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