Photosensitization and controlled photosensitization with BODIPY dyes

被引：347
作者：
Turksoy, Abdurrahman [1 ]
Yildiz, Deniz [1 ]
Akkaya, Engin U. [1 ,2 ]
机构：
[1] Bilkent Univ, Dept Chem, TR-06800 Ankara, Turkey
[2] Bilkent Univ, UNAM Natl Nanotechnol Res Ctr, TR-06800 Ankara, Turkey
来源：
COORDINATION CHEMISTRY REVIEWS | 2019年 / 379卷
关键词：
Photosensitization; BODIPY; Photodynamic therapy; Reactive oxygen species; Selective photosensitizers; SINGLET OXYGEN GENERATION; ORGANIC TRIPLET PHOTOSENSITIZERS; PHOTODYNAMIC THERAPY; EXCITED-STATES; IN-VIVO; DISTYRYL-BORADIAZAINDACENES; EFFICIENT PHOTOSENSITIZERS; PHOTORADIATION THERAPY; PHOTOREDOX CATALYSIS; ELECTRON-TRANSFER;
D O I：
10.1016/j.ccr.2017.09.029
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Highly versatile BODIPY dyes proved themselves to be very useful as photosensitizers. These dyes can be derivatized to absorb essentially anywhere in the visible the near IR region of the spectrum. As a result of their diverse reactivity, singlet oxygen generation efficiency can be modulated very precisely, leading to a number of selective photosensitizers for photodynamic therapy. Among the biologically relevant modulators, glutathione concentration and pH received particular attention. In this review, we highlight modulatable BODIPY-based photodynamic photosensitizers, and various synthetically useful chemical reactions triggered by singlet oxygen and other reactive oxygen species generated by BODIPY-based photosensitizers.(C) 2017 Elsevier B.V. All rights reserved.
引用
收藏
页码：47 / 64
页数：18
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