Direct Hydrogenation of a Broad Range of Amides under Base-free Conditions using an Efficient and Selective Ruthenium(II) Pincer Catalyst

被引：28

作者：

Wang, Zheng ^{[1
,2
,3
,4
]}

Li, Yong ^{[1
]}

Liu, Qing-bin ^{[1
]}

Solan, Gregory A. ^{[2
,3
,5
]}

Ma, Yanping ^{[2
,3
]}

Sun, Wen-Hua ^{[2
,3
,4
]}

机构：

[1] Hebei Normal Univ, Coll Chem & Mat Sci, Shijiazhuang 050024, Hebei, Peoples R China

[2] Chinese Acad Sci, Key Lab Engn Plast, Inst Chem, Beijing 100190, Peoples R China

[3] Chinese Acad Sci, Beijing Natl Lab Mol Sci, Inst Chem, Beijing 100190, Peoples R China

[4] Univ Chinese Acad Sci, CAS Res Educ Ctr Excellence Mol Sci, Beijing 100049, Peoples R China

[5] Univ Leicester, Dept Chem, Univ Rd, Leicester LE1 7RH, Leics, England

来源：

CHEMCATCHEM | 2017年 / 9卷 / 22期

基金：

中国国家自然科学基金;

关键词：

amides; amines; homogeneous catalysis; hydrogenation; ruthenium; METAL-LIGAND COOPERATION; HOMOGENEOUS HYDROGENATION; SECONDARY ALCOHOLS; TERTIARY AMIDES; MILD CONDITIONS; AMINES; REDUCTION; COMPLEX; ACID; DEHYDROGENATION;

D O I：

10.1002/cctc.201700952

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The ruthenium(II) complex, [fac-PNHN]RuH((1)-BH4)(CO) (B; PNHN=8-(2-diphenylphosphinoethyl)aminotrihydroquinoline), is a highly versatile and effective catalyst (loadings of 0.1-1mol%) for the hydrogenation of a multitude of amides, which include primary, secondary, and tertiary amides, to give their corresponding alcohols and amines in high yields under base-free conditions. All products were confirmed by using GC and GC-MS.

引用

页码：4275 / 4281

页数：7