Thyroid hormone-responsive genes mediate otolith growth and development during flatfish metamorphosis

被引:12
作者
Wang, X. [2 ]
Tan, Y. [2 ]
Sievers, Q. [2 ]
Sievers, B. [2 ]
Lee, M. [2 ]
Burrall, K. [1 ]
Schreiber, A. M. [1 ,2 ]
机构
[1] St Lawrence Univ, Dept Biol, Canton, NY 13617 USA
[2] Carnegie Inst, Dept Embryol, Baltimore, MD 21210 USA
来源
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY | 2011年 / 158卷 / 01期
关键词
Thyroid hormone; Metamorphosis; Flatfish; Otolith; Vestibular; Inner ear; MOUSE INNER-EAR; POSTURAL ORIENTATION; OTOCONIAL AGENESIS; MATRIX PROTEINS; FLOUNDER LARVAE; STAGE; LEPTOCEPHALI; OTOPETRIN-1; EXPRESSION; AUSTRALIS;
D O I
10.1016/j.cbpa.2010.10.014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Flatfish begin life as up-right swimming, bilaterally symmetrical larvae that metamorphose into asymmetrically shaped juveniles that swim with a highly lateralized posture. We have previously shown that TH induces abrupt growth and mineralization of one component of the vestibular system, the otoliths, during early larval development and metamorphosis. Here we report that four of five vestibular-specific genes that we tested (alpha-tectorin, otogelin, otolith matrix protein, and otopetrins I and 2 that are known to be associated with otolith development in other vertebrates are up-regulated 1.5- to 7-fold in larval flatfish during spontaneous metamorphosis and/or following 72 h of TH treatment. These findings suggest that otolith growth and development are mediated by diverse TH-responsive genes during flatfish metamorphosis. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码:163 / 168
页数:6
相关论文
共 50 条
  • [21] Thyroid hormone receptor expression during metamorphosis of Atlantic halibut (Hippoglossus hippoglossus)
    Galay-Burgos, Malyka
    Power, Deborah M.
    Llewellyn, Lynda
    Sweeney, Glen E.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2008, 281 (1-2) : 56 - 63
  • [22] Change of body height is regulated by thyroid hormone during metamorphosis in flatfishes and zebrafish
    Xu, Juan
    Ke, Zhonghe
    Xia, Jianhong
    He, Fang
    Bao, Baolong
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2016, 236 : 9 - 16
  • [23] Role of Thyroid Hormone in Dynamic Variation of gdf6a Gene during Metamorphosis of Paralichthys olivaceus
    Shi, Yaxin
    Qiu, Junqiang
    Li, Xike
    Lin, Yue
    Li, Wenjuan
    Hou, Jilun
    Fu, Yuanshuai
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (01)
  • [24] Synthetic hormone-responsive transcription factors can monitor and reprogram plant development
    Khakharn, Arjun
    Leydon, Alexander R.
    Lemmex, Andrew C.
    Klavins, Eric
    Nemhauser, Jennifer L.
    ELIFE, 2018, 7
  • [25] Distinct Expression Profiles of Three Melatonin Receptors during Early Development and Metamorphosis in the Flatfish Solea senegalensis
    Lan-Chow-Wing, Olivier
    Confente, Francesca
    Herrera-Perez, Patricia
    Isorna, Esther
    Chereguini, Olvido
    del Carmen Rendon, Maria
    Falcon, Jack
    Munoz-Cueto, Jose A.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2014, 15 (11): : 20789 - 20799
  • [26] Thyroid hormone deiodinase type 2 mRNA levels in sea lamprey (Petromyzon marinus) are regulated during metamorphosis and in response to a thyroid challenge
    Stilborn, S. Salina M.
    Manzon, Lori A.
    Schauenberg, Jennifer D.
    Manzon, Richard G.
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2013, 183 : 63 - 68
  • [27] Cloning of Atlantic halibut growth hormone receptor genes and quantitative gene expression during metamorphosis
    Hildahl, Jon
    Sweeney, Glen
    Galay-Burgos, Malyka
    Einarsdottir, Ingibjorg Eir
    Bjornsson, Bjorn Thrandur
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2007, 151 (02) : 143 - 152
  • [28] Thyroid Hormone Signaling Is Required for Dynamic Variation in Opsins in the Retina during Metamorphosis of the Japanese Flounder (Paralichthys olivaceus)
    Shi, Yaxin
    Shi, Yang
    Ji, Wenyao
    Li, Xike
    Shi, Zhiyi
    Hou, Jilun
    Li, Wenjuan
    Fu, Yuanshuai
    BIOLOGY-BASEL, 2023, 12 (03):
  • [29] Expression of marker genes during otolith development in medaka
    Nemoto, Yoshiyuki
    Chatani, Masahiro
    Inohaya, Keiji
    Hiraki, Yuji
    Kudo, Akira
    GENE EXPRESSION PATTERNS, 2008, 8 (02) : 92 - 95
  • [30] A model of transcriptional and morphological changes during thyroid hormone-induced metamorphosis of the axolotl
    Page, Robert B.
    Monaghan, James R.
    Walker, John A.
    Voss, S. Randal
    GENERAL AND COMPARATIVE ENDOCRINOLOGY, 2009, 162 (02) : 219 - 232