Hypoglycemic and antidiabetic activities on the stem bark aqueous and ethanol extracts of Musanga cecropioides in normal and alloxan-induced diabetic rats

被引：17

作者：

Adeneye, A. A.

Ajagbonna, O. P.

Ayodele, O. W.

机构：

[1] Lagos State Univ Med, Dept Pharmacol, Ikeja, Nigeria

[2] Usman Danfodiyo Univ, Fac Med Vet, Dept Vet Physiol & Pharmacol, Sokoto, Nigeria

[3] Lagos State Univ, Fac Sci, Dept Biochem, Lagos, Nigeria

来源：

FITOTERAPIA | 2007年 / 78卷 / 7-8期

关键词：

Musanga cecropioides; hypoglycemic; antidiabetic; stem bark;

D O I：

10.1016/j.fitote.2007.05.001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Daily oral administration of the aqueous and ethanolic extracts of Musanga cecropioides stem bark in normal and diabetic rats at doses of 250, 500 and 1000 mg/kg/day, for 14 days significantly lowered the fasting plasma glucose levels in normal and alloxan-induced diabetic rats in dose-dependent fashion. The ethanol extract induced more significant antidiabetic effect than the aqueous extract. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：502 / 505

页数：4

共 19 条

[1] The hypotensive mechanisms for the aqueous stem bark extract of Musanga cecropioides in Sprague-Dawley rats [J].