Interdisciplinary expert consensus on innovations in imaging diagnostics and radionuclide-based therapies for advanced prostate cancer

被引：2

作者：

Beyersdorff, Dirk ^{[1
]}

Rahbar, Kambiz ^{[2
]}

Essler, Markus ^{[3
]}

Ganswindt, Ute ^{[4
]}

Grosu, Anca-Ligia ^{[5
]}

Gschwend, Juergen E. ^{[6
]}

Miller, Kurt ^{[7
]}

Scheidhauer, Klemens ^{[8
]}

Schlemmer, Heinz-Peter ^{[9
]}

Wolff, Johannes Maria ^{[10
]}

Krause, Bernd Joachim ^{[11
]}

机构：

[1] Univ Klinikum Hamburg Eppendorf, Klin & Poliklin Diagnost & Intervent Radiol & Nuk, Hamburg, Germany

[2] Univ Klinikum Munster, Klin Nukl Med, Munster, Germany

[3] Univ Klinikum Bonn, Klin & Poliklin Nukl Med, Bonn, Germany

[4] Med Univ Innsbruck, Univ Klin Strahlentherapie & Radioonkol, Innsbruck, Austria

[5] Univ Klinikum Freiburg, Klin Strahlenheilkunde, Freiburg, Germany

[6] Klinikum Rechts Der Isar, Urol Klin & Poliklin, Munich, Germany

[7] Charite Univ Med Berlin, Klin Urol, Berlin, Germany

[8] Klinikum Rechts Der Isar, Nukl Med, Munich, Germany

[9] Univ Klinikum Heidelberg, Abt Radiol, Heidelberg, Germany

[10] Paracelsus Klin Golzheim, Urol, Dusseldorf, Germany

[11] Univ Med Rostock, Klin & Poliklin Nukl Med, Schillingallee 35, D-18057 Rostock, Germany

来源：

UROLOGE | 2021年 / 60卷 / 12期

关键词：

Prostate cancer; Castration resistance; PSMA-PET; CT; Radium-223; Lutetium-177-PSMA; RADIOLIGAND THERAPY; PET/CT; MRI;

D O I：

10.1007/s00120-021-01598-2

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Background Numerous diagnostic and therapeutic innovations in the treatment of advanced prostate cancer, both in the hormone-sensitive and in the castration-resistant situation, recently led to a new orientation in the management of this tumor. However, there are potential indications beyond the ones covered by the S3 guideline on early detection, diagnosis and therapy of prostate cancer in clinical care that might be helpful for patients. Objectives Since July 2018, an interdisciplinary group of experts from nuclear medicine, radiologists, radio-oncologists and urologists developed a consensus paper on state-of-the-art innovations in imaging diagnostics and radionuclide-based therapies for advanced prostate cancer. Conclusions Provided by the working group are suggestions and strategies to improve the implementation of new imaging techniques such as multiparametric magnetic resonance imaging (mpMRI), PSMA-PET/CT (prostate-specific membrane antigen-positron emission tomography/computed tomography) and innovative therapeutic options (radium-223 dichloride, lutetium-177-PSMA) in the complex treatment of metastatic castration-resistant prostate cancer (mCRPC).

引用

页码：1579 / 1585

页数：7

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