GMDD: a database of GMO detection methods

被引：84

作者：

Dong, Wei ^{[1
]}

Yang, Litao ^{[1
]}

Shen, Kailin ^{[2
]}

Kim, Banghyun ^{[3
]}

Kleter, Gijs A. ^{[4
]}

Marvin, Hans J. P. ^{[4
]}

Guo, Rong ^{[5
]}

Liang, Wanqi ^{[1
]}

Zhang, Dabing ^{[1
]}

机构：

[1] Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Minist Educ,GMO Detect Lab, Key Lab Microbial Metab,SJTU Bor Luh Food Safety, Shanghai 200240, Peoples R China

[2] Shanghai Fisheries Univ, Shanghai 200090, Peoples R China

[3] Korea Food & Drug Adm, Seoul 122704, South Korea

[4] Univ Wageningen & Res Ctr, Inst Food Safety, RIKILT, NL-6708 PD Wageningen, Netherlands

[5] Shanghai Univ, Shanghai 200072, Peoples R China

来源：

BMC BIOINFORMATICS | 2008年 / 9卷 / 1期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1186/1471-2105-9-260

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Background: Since more than one hundred events of genetically modified organisms (GMOs) have been developed and approved for commercialization in global area, the GMO analysis methods are essential for the enforcement of GMO labelling regulations. Protein and nucleic acid-based detection techniques have been developed and utilized for GMOs identification and quantification. However, the information for harmonization and standardization of GMO analysis methods at global level is needed. Results: GMO Detection method Database (GMDD) has collected almost all the previous developed and reported GMOs detection methods, which have been grouped by different strategies (screen-, gene-, construct-, and event-specific), and also provide a user-friendly search service of the detection methods by GMO event name, exogenous gene, or protein information, etc. In this database, users can obtain the sequences of exogenous integration, which will facilitate PCR primers and probes design. Also the information on endogenous genes, certified reference materials, reference molecules, and the validation status of developed methods is included in this database. Furthermore, registered users can also submit new detection methods and sequences to this database, and the newly submitted information will be released soon after being checked. Conclusion: GMDD contains comprehensive information of GMO detection methods. The database will make the GMOs analysis much easier.

引用

页数：8

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