Isariotins G-J from cultures of the Lepidoptera pathogenic fungus Isaria tenuipes

被引:18
作者
Bunyapaiboonsri, Taridaporn [1 ]
Yoiprommarat, Seangaroon [1 ]
Srisanoh, Urarat [1 ]
Choowong, Wilunda [1 ]
Tasanathai, Kanoksri [1 ]
Hywel-Jones, Nigel L. [1 ]
Luangsa-ard, J. Jennifer [1 ]
Isaka, Masahiko [1 ]
机构
[1] Natl Ctr Genet Engn & Biotechnol BIOTEC, Klongluang 12120, Pathumthani, Thailand
关键词
Isaria tenuipes; Paecilomyces tenuipes; Isariotin; Antimalarial activity; Cytotoxicity; PAECILOMYCES-TENUIPES; ENTOMOPATHOGENIC FUNGUS; TRICHOTHECANES; BCC-1614;
D O I
10.1016/j.phytol.2011.04.018
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Four new alkaloids isariotins G-J (1-4), together with the known isariotins, were isolated from cultures of the Lepidoptera pathogenic fungus Isaria tenuipes. The structures were elucidated on the basis of NMR spectroscopic and mass spectrometry data. Compounds 1-4 exhibited antimalarial and cytotoxic activities. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:283 / 286
页数:4
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