Iron-Catalyzed 1,2-Selective Hydroboration of N-Heteroarenes

被引：96

作者：

Zhang, Fanjun ^{[1
]}

Song, Heng ^{[1
]}

Zhuang, Xuewen ^{[1
]}

Tung, Chen-Ho ^{[1
]}

Wang, Wenguang ^{[1
]}

机构：

[1] Shandong Univ, Sch Chem & Chem Engn, 27 South Shanda Rd, Jinan 250100, Shandong, Peoples R China

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 139卷 / 49期

基金：

中国国家自然科学基金;

关键词：

H BOND ACTIVATION; BIOMIMETIC ASYMMETRIC HYDROGENATION; REGIOSELECTIVE 1,4-HYDROBORATION; ORGANIC-SYNTHESIS; HYDRIDE TRANSFER; HANTZSCH ESTERS; PINCER COMPLEX; PYRIDINES; HYDROSILYLATION; DINITROGEN;

D O I：

10.1021/jacs.7b11416

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A N-2-bridged diiron complex [Cp*-(Ph2PC6H4S)Fe](2)(mu-N-2) (1) has been found to catalyze the hydroboration of N-heteroarenes with pinacolborane, giving N-borylated 1,2-reduced products with high regioselectivity. The catalysis is initiated by coordination of N-heteroarenes to the iron center, while the B-H bond cleavage is the rate-determining step.

引用

页码：17775 / 17778

页数：4

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