Magnetite graphene oxide modified with beta-cyclodextrin as an effective adsorbent for the removal of methotrexate and doxorubicin hydrochloride from water

The purpose of this investigation was to analyze the performance of magnetite graphene oxide modified with beta-cyclodextrin (GO@Fe3O4@beta-CD) for adsorption of methotrexate (MTX) and doxorubicin (DOX) from aqueous solutions. Characterization of GO@Fe3O4@beta-CD was carried out using some methods. The perfect conditions for the adsorption of MTX and DOX were 7.0, 45 min, 20 mg, and 25 degrees C for solution pH, contact time, adsorbent dose, and temperature, respectively, with removal efficiency values of 97.8% and 98.5% for MTX and DOX, respectively. The adsorption kinetic of MTX and DOX via GO@Fe3O4@beta-CD followed pseudo second-order (PSO) model, while the adsorption isotherm obeyed Langmuir model by monolayer adsorption with maximum adsorption capacities of 198.5 and 204.5 mg g(-1) for MTX and DOX, respectively. Therefore, it could be argued that HCl and 0.1 mol L-1 NaOH would reflect adequate elution properties for GO@Fe3O4@beta-CD recovery.