Parallel Evolution of Bacillus thuringiensis Toxin Resistance in Lepidoptera

被引:242
|
作者
Baxter, Simon W. [1 ]
Badenes-Perez, Francisco R. [2 ]
Morrison, Anna [1 ]
Vogel, Heiko [3 ]
Crickmore, Neil [4 ]
Kain, Wendy [5 ]
Wang, Ping [5 ]
Heckel, David G. [3 ]
Jiggins, Chris D. [1 ]
机构
[1] Univ Cambridge, Dept Zool, Cambridge CB2 3EJ, England
[2] Inst Ciencias Agr, Madrid 28006, Spain
[3] Max Planck Inst Chem Ecol, Dept Entomol, D-07745 Jena, Germany
[4] Univ Sussex, Dept Biochem, Falmer BN1 9QG, England
[5] Cornell Univ, New York State Agr Expt Stn, Dept Entomol, Geneva, NY 14456 USA
基金
英国生物技术与生命科学研究理事会;
关键词
DIAMONDBACK MOTH; PLUTELLA-XYLOSTELLA; TRICHOPLUSIA-NI; INSECT RESISTANCE; CRYSTAL PROTEINS; BINDING-PROTEINS; CABBAGE-LOOPER; BT TOXINS; CRY1AC; IDENTIFICATION;
D O I
10.1534/genetics.111.130971
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
引用
收藏
页码:675 / U814
页数:9
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