Antibiotic adverse reactions and drug interactions

被引：98
作者：
Granowitz, Eric V. [1 ]
Brown, Richard B. [1 ]
机构：
[1] Tufts Univ, Sch Med, Div Infect Dis, Baystate Med Ctr, Springfield, MA 01199 USA
来源：
CRITICAL CARE CLINICS | 2008年 / 24卷 / 02期
关键词：
D O I：
10.1016/j.ccc.2007.12.011
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
When contemplating antibiotic use, intensivists must consider possible beneficial and harmful drug interactions. After antibiotics are instituted, adverse reactions must be anticipated. Acute illness, comorbidities, and concurrent medications affect the presentation and management of antibiotic-related adverse events. Intensivists should use the fewest possible antibiotics, carefully choosing agents that maximize antimicrobial activity and minimize potential drug interactions and adverse reactions.
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页码：421 / +
页数：23
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