Comparison of the 1-Year Visual and Anatomical Outcomes between Subthreshold Red (670 nm) and Yellow (577 nm) Micro-Pulse Laser Treatment for Diabetic Macular Edema

被引:15
作者
Kikushima, Wataru [1 ]
Shijo, Taiyo [1 ]
Furuhata, Yukiko [1 ]
Sakurada, Yoichi [1 ]
Kashiwagi, Kenji [1 ]
机构
[1] Univ Yamanashi, Dept Ophthalmol, Chuo, Yamanashi 4093898, Japan
关键词
diabetic macular edema; subthreshold red micropulse laser treatment; subthreshold yellow micropulse laser treatment; diabetic retinopathy; DIODE-LASER; ANTI-VEGF; PHOTOCOAGULATION; INTRAVITREAL; RANIBIZUMAB; RETINOPATHY; INJECTION; EFFICACY; THERAPY; SAFETY;
D O I
10.3390/ph14111100
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
We investigated the efficacy and safety of red (670 nm) subthreshold micropulse laser (SMPL) treatment for diabetic macular edema (DME) and compared the 1-year treatment outcomes of red and yellow (577 nm) SMPL for DME. A medical chart review was performed in 43 consecutive eyes of 35 patients who underwent red or yellow SMPL treatment for DME and were followed up for 12 months. There were 26 and 17 eyes in the yellow and red SMPL groups, respectively. The mean best-corrected visual acuity (BCVA) was maintained throughout the follow-up period of 12 months in the yellow and red SMPL groups (p = 0.39, p = 0.70, respectively). The central retinal thickness (CRT) measured by spectral-domain optical coherence tomography (SD-OCT) was significantly decreased at 12 months from baseline in the yellow and red SMPL groups (p = 0.047, p = 0.03, respectively). Although the amount of CRT reduction in the red SMPL group was significantly greater than that in the yellow SMPL group at 8 months from baseline (p = 0.02), the significance disappeared at the final follow-up period (p = 0.44). The red SMPL maintained the BCVA in patients with center-involving DME. The mean CRT in the red SMPL group significantly decreased, and the amount of CRT reduction was equivalent to that in the yellow SMPL group.
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页数:11
相关论文
共 33 条
[1]   Subthreshold micropulse laser versus intravitreal anti-VEGF for diabetic macular edema patients with relatively better visual acuity [J].
Akkaya, Sezen ;
Acikalin, Banu ;
Dogan, Yusuf Emre ;
Coban, Faith .
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY, 2020, 13 (10) :1606-1611
[2]   Comparison of short-pulse subthreshold (532 nm) and infrared micropulse (810 nm) macular laser for diabetic macular edema [J].
Al-Barki, Abdulrahman ;
Al-Hijji, Lamia ;
High, Robin ;
Schatz, Patrik ;
Do, Diana ;
Nguyen, Quan D. ;
Luttrull, Jeffrey K. ;
Kozak, Igor .
SCIENTIFIC REPORTS, 2021, 11 (01)
[3]   Outcomes with As-Needed Ranibizumab after Initial Monthly Therapy Long-Term Outcomes of the Phase III RIDE and RISE Trials [J].
Boyer, David S. ;
Nguyen, Quan Dong ;
Brown, David M. ;
Basu, Karen ;
Ehrlich, Jason S. .
OPHTHALMOLOGY, 2015, 122 (12) :2504-+
[4]   Three-Year, Randomized, Sham-Controlled Trial of Dexamethasone Intravitreal Implant in Patients with Diabetic Macular Edema [J].
Boyer, David S. ;
Yoon, Young Hee ;
Belfort, Rubens, Jr. ;
Bandello, Francesco ;
Maturi, Raj K. ;
Augustin, Albert J. ;
Li, Xiao-Yan ;
Cui, Harry ;
Hashad, Yehia ;
Whitcup, Scott M. .
OPHTHALMOLOGY, 2014, 121 (10) :1904-1914
[5]   Five-Year Outcomes of Ranibizumab With Prompt or Deferred Laser Versus Laser or Triamcinolone Plus Deferred Ranibizumab for Diabetic Macular Edema [J].
Bressler, Susan B. ;
Glassman, Adam R. ;
Almukhtar, Talat ;
Bressler, Neil M. ;
Ferris, Frederick L. ;
Googe, Joseph M., Jr. ;
Gupta, Shailesh K. ;
Jampol, Lee M. ;
Melia, Michele ;
Wells, John A., III .
AMERICAN JOURNAL OF OPHTHALMOLOGY, 2016, 164 :57-68
[6]   Comparison of Subthreshold 577 and 810 nm Micropulse Laser Effects on Heat-Shock Protein Activation Kinetics: Implications for Treatment Efficacy and Safety [J].
Chang, David B. ;
Luttrull, Jeffrey K. .
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY, 2020, 9 (05)
[7]   Diabetic retinopathy [J].
Cheung, Ning ;
Mitchell, Paul ;
Wong, Tien Yin .
LANCET, 2010, 376 (9735) :124-136
[8]  
Dorin Giorgio, 2004, Semin Ophthalmol, V19, P62, DOI 10.1080/08820530490884173
[9]   The treatment of macular disease using a micropulsed and continuous wave 810-nm diode laser [J].
Friberg, TR ;
Karatza, EC .
OPHTHALMOLOGY, 1997, 104 (12) :2030-2038
[10]   Micropulse Laser Treatment of Retinal Diseases [J].
Gawecki, Maciej .
JOURNAL OF CLINICAL MEDICINE, 2019, 8 (02)