Supported lipid bilayer membrane arrays on micro-patterned ITO electrodes

被引：10
|
作者：
Wang, Xuejing [1 ]
Zhang, Ying [1 ]
Bi, Hongmei [1 ]
Han, Xiaojun [1 ]
机构：
[1] Harbin Inst Technol, State Key Lab Urban Water Resource & Environm, Sch Chem & Chem Engn, 92 West Da Zhi St, Harbin 150001, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 76期
基金：
中国国家自然科学基金;
关键词：
SELF-ASSEMBLED MONOLAYERS; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; BIOMIMETIC MEMBRANES; PHOSPHOLIPID-BILAYERS; ELECTRICAL-PROPERTIES; PHASE-SEPARATION; CELL-ADHESION; SURFACES; GOLD; CONSTRUCTION;
D O I：
10.1039/c6ra10294h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Lipid bilayer arrays were formed on ITO electrodes coated with a patterned self-assembled trimethoxy(octadecyl) silane monolayer (TODS-SAM). The TODS-SAM was patterned by deep UV (254 nm) irradiation through a quartz mask to create the patterned SAM modified ITO surface. Field-emission scanning electron microscopy was applied to characterize the patterned TODS SAM modified ITO. The lipid bilayer arrays were characterized by fluorescence microscopy, cyclic voltammetry and electrochemical impedance spectroscopy. With this bilayer array platform both the fluorescence microscopy and electrochemical detection can be realized to explore the biophysical properties of the cell membrane.
引用
收藏
页码：72821 / 72826
页数：6
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