Background: The WHOQOL-BREF is widely used to measure quality of life.Aims: The goal of the present study was to use the questionnaire in a doctoral study.Methods: We studied all the instructions provided by the WHO.Results: In the Danish version of the WHOQOL-BREF there is a discrepancy between the negatively phrased question 9 and both the syntax file and the verbal instructions for coding the data provided by the WHO.Conclusions: This is a notification of possible error interpretations in projects that use the questionnaire. This could be corrected by manual correction in the coding process or by changing the negatively phrased question 9.
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