Montiporic acids A and B, cytotoxic and antimicrobial polyacetylene carboxylic acids from eggs of the scleractinian coral Montipora digitata

被引：47

作者：

Fusetani, N ^{[1
]}

Toyoda, T ^{[1
]}

Asai, N ^{[1
]}

Matsunaga, S ^{[1
]}

Maruyama, T ^{[1
]}

机构：

[1] SHIMIZU LABS,MARINE BIOTECHNOL INST,SHIZUOKA 424,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1996年 / 59卷 / 08期

关键词：

D O I：

10.1021/np9604036

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new polyacetylene carboxylic acids, montiporic acids A (1) and B (2), have been isolated from the eggs of the scleractinian coral Montipora digitata and their structures elucidated on the basis of spectroscopic data. They exhibited antimicrobial activity against Escherichia coli and cytotoxicity against P-388 murine leukemia cells.

引用

页码：796 / 797

页数：2

共 10 条

[1]

ARAI T, 1993, CORAL REEFS, V12, P71

[2] THE CHEMISTRY AND CHEMICAL ECOLOGY OF OCTOCORALS (COELENTERATA, ANTHOZOA, OCTOCORALLIA) [J].

COLL, JC .

CHEMICAL REVIEWS, 1992, 92 (04) :613-631

[3] CHEMICAL ASPECTS OF MASS SPAWNING IN CORALS .1. SPERM-ATTRACTANT MOLECULES IN THE EGGS OF THE SCLERACTINIAN CORAL MONTIPORA-DIGITATA [J].

COLL, JC ;

BOWDEN, BF ;

MEEHAN, GV ;

KONIG, GM ;

CARROLL, AR ;

TAPIOLAS, DM ;

ALINO, PM ;

HEATON, A ;

DENYS, R ;

LEONE, PA ;

MAIDA, M ;

ACERET, TL ;

WILLIS, RH ;

BABCOCK, RC ;

WILLIS, BL ;

FLORIAN, Z ;

CLAYTON, MN ;

MILLER, RL .

MARINE BIOLOGY, 1994, 118 (02) :177-182

[4]

FAULKNER DJ, 1995, NAT PROD REP, V12, P233

[5] BIOACTIVE MARINE METABOLITES .15. ISOLATION OF APLYSINOPSIN FROM THE SCLERACTINIAN CORAL TUBASTREA-AUREA AS AN INHIBITOR OF DEVELOPMENT OF FERTILIZED SEA-URCHIN EGGS [J].

FUSETANI, N ;

ASANO, M ;

MATSUNAGA, S ;

HASHIMOTO, K .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1986, 85 (04) :845-846

[6] BIOACTIVE POLYACETYLENES FROM STONY CORALS [J].

HIGA, T ;

TANAKA, J ;

KOHAGURA, T ;

WAUKE, T .

CHEMISTRY LETTERS, 1990, (01) :145-148

[7] Three new cytotoxic sesterterpenes from the marine sponge Hyrtios cf erectus [J].

Ryu, G ;

Matsunaga, S ;

Fusetani, N .

JOURNAL OF NATURAL PRODUCTS, 1996, 59 (05) :515-517

[8] TUBASTRINE, A NEW GUANIDINOSTYRENE FROM THE CORAL TUBASTREA-AUREA [J].

SAKAI, R ;

HIGA, T .

CHEMISTRY LETTERS, 1987, (01) :127-128

[9]

Sammarco P.W., 1988, Bioorganic Marine Chemistry, V2, P87

[10]

SCOTT AI, 1964, INTERPRETATION ULTRA, P283

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