Novel selenium-containing acenaphtho[1,2-b]pyrrole derivatives: Synthesis and bioactivity

被引:2
作者
Wang, Jisong [1 ]
Yang, Fuli [1 ]
Zheng, Liang [2 ]
Ren, Gang [1 ]
Qi, Jiude [1 ]
Wang, Zhijun [3 ]
Zhao, Liwei [3 ]
机构
[1] Laiwu City Peoples Hosp, Dept Oncol, Laiwu, Shandong, Peoples R China
[2] Laiwu City Peoples Hosp, Dept Resp, Laiwu, Shandong, Peoples R China
[3] ShandongWego Pharmaceut Co Ltd, Xingshan Rd 20, Laiwu, Shandong, Peoples R China
关键词
Selenium; acenaphtho[1,2-b]pyrrole; cytotoxicity; cancer; BIOLOGICAL-ACTIVITY; ORGANOSELENIUM; INHIBITORS; DESIGN; AGENTS; BCL-2;
D O I
10.1080/10426507.2015.1072187
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Seven novel selenium-containing,aceriaphtho[1,2-h]pyrrole derivativesre designed arid synthesized and heir cytotoxic effects were evaluated by the MTT tetrazollum dye assay,Two compounds presented good anticancer activities.
引用
收藏
页码:715 / 718
页数:4
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