COVID-19 and dysnatremia: A comparison between COVID-19 and non-COVID-19 respiratory illness

被引:9
|
作者
Voets, Philip J. G. M. [1 ,2 ]
Frolke, Sophie C. [2 ]
Vogtlander, Nils P. J. [1 ]
Kaasjager, Karin A. H. [2 ]
机构
[1] Gelre Hosp, Dept Nephrol, Albert Schweitzerlaan 31, NL-7334 DZ Apeldoorn, Netherlands
[2] Univ Med Ctr Utrecht, Dept Internal Med, Utrecht, Netherlands
来源
SAGE OPEN MEDICINE | 2021年 / 9卷
关键词
COVID-19; SARS coronavirus; hyponatremia; hypernatremia; dysnatremia; HYPERNATREMIA; HYPONATREMIA; PREVALENCE;
D O I
10.1177/20503121211027778
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: To investigate the occurrence of disorders of water and sodium balance in COVID-19 in our clinic. Methods: In this retrospective chart review, patients were included if a polymerase chain test result for SARS-CoV-2 was obtained and if at least one plasma sodium concentration measurement was obtained during the period from March to June 2020. The occurrences of hyponatremia and hypernatremia were compared between 193 SARS-CoV-2-positive and 138 SARS-CoV-2-negative patients. A chi(2) test was used to determine statistical significance, and the corresponding p-values were calculated. Results: Hypernatremia was significantly more frequently observed in COVID-19 patients, in 38% (74 of 193), versus only 8% in SARS-CoV-2-negative patients (11 of 138) (p < 0.01). Hyponatremia was observed in 34% of the included COVID-19 patients (65 of 193) versus 24% of SARS-CoV-2-negative patients (33 of 138). In 12% of all COVID-19 patients (23 of 193), both hyponatremia and hypernatremia were observed at some point during their admission. Among the non-COVID-19 patients, only 4% showed these plasma sodium concentration fluctuations (5 of 138). The mortality rate among the hospitalized COVID-19 patients was 23% (45 of 193). Correcting for double-counting, more than 71% (32 of 45) of the deceased COVID-19 patients developed dysnatremia (hyponatremia, hypernatremia or both) versus 57% (84 out of 148) of the surviving COVID-19 patients. Conclusion: Disorders of water and sodium balance-and especially hypernatremia-seem to be a common occurrence in COVID-19 patients. This has important implications for the treatment of COVID-19 patients.
引用
收藏
页数:5
相关论文
共 50 条
  • [31] Differences between radiological findings of COVID-19 and non-COVID-19 infections in pediatric patients
    Kuzan, Beyza Nur
    Aslan, Bulent
    Kuzan, Taha Yusuf
    Yagci, Aysegul Karahasan
    Cimsit, Nuri cagatay
    WORLD JOURNAL OF PEDIATRICS, 2021, 17 (01) : 79 - 84
  • [32] Cardiovascular outcomes between COVID-19 and non-COVID-19 pneumonia: a nationwide cohort study
    Lee, Min-Taek
    Baek, Moon Seong
    Kim, Tae Wan
    Jung, Sun-Young
    Kim, Won-Young
    BMC MEDICINE, 2023, 21 (01)
  • [33] Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress Syndrome
    Metkus, Thomas S.
    Sokoll, Lori J.
    Barth, Andreas S.
    Czarny, Matthew J.
    Hays, Allison G.
    Lowenstein, Charles J.
    Michos, Erin D.
    Nolley, Eric P.
    Post, Wendy S.
    Resar, Jon R.
    Thiemann, David R.
    Trost, Jeffrey C.
    Hasan, Rani K.
    CIRCULATION, 2021, 143 (06) : 553 - 565
  • [34] Differences between radiological findings of COVID-19 and non-COVID-19 infections in pediatric patients
    Beyza Nur Kuzan
    Bülent Aslan
    Taha Yusuf Kuzan
    Ayşegül Karahasan Yağcı
    Nuri Çagatay Çimşit
    World Journal of Pediatrics, 2021, 17 : 79 - 84
  • [35] Fewer non-COVID-19 respiratory tract infections and gastrointestinal infections during the COVID-19 pandemic
    Tanislav, Christian
    Kostev, Karel
    JOURNAL OF MEDICAL VIROLOGY, 2022, 94 (01) : 298 - 302
  • [36] Comparison of sleep quality among COVID-19 patients and non-COVID-19 population in Pakistan: A cross sectional study during the COVID-19 pandemic
    Malik, Muna
    Atiq, Ayesha
    Tahir, Muhammad Junaid
    Akhtar, Fahd Kamal
    Malik, Muhammad Irfan
    Hassan, Wardah
    Khan, Fatima Muhammad Asad
    Akram, Iqra
    Manhas, Noraiz
    Ullah, Irfan
    Asghar, Muhammad Sohaib
    ANNALS OF MEDICINE AND SURGERY, 2022, 78
  • [37] Characteristics and Comparison of 32 COVID-19 and Non-COVID-19 Ischemic Strokes and Historical Stroke Patients
    Akhtar, Naveed
    Ben Abid, Fatma
    Kamran, Saadat
    Singh, Rajvir
    Imam, Yahia
    AlJerdi, Salman
    AlMaslamani, Muna
    Shuaib, Ashfaq
    JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2021, 30 (01)
  • [38] Risk perception of emergency medical technicians in biological disasters: a comparison between COVID-19 and Non-COVID-19 cases
    Mohammad Azim Mahmodi
    Ayob Akbari
    Seyyed Mohammad Reza Hosseini
    Zahra Amouzeshi
    BMC Emergency Medicine, 25 (1)
  • [39] Comparison of sleep quality among COVID-19 patients and non-COVID-19 population in Pakistan: A cross sectional study during the COVID-19 pandemic
    Malik, Muna
    Atiq, Ayesha
    Tahir, Muhammad Junaid
    Akhtar, Fahd Kamal
    Malik, Muhammad Irfan
    Hassan, Wardah
    Khan, Fatima Muhammad Asad
    Akram, Iqra
    Manhas, Noraiz
    Ullah, Irfan
    Asghar, Muhammad Sohaib
    ANNALS OF MEDICINE AND SURGERY, 2022, 78
  • [40] Nursing performance in COVID-19 and non-COVID-19 units: Implications for occupational health
    Ampos, Larissa Fonseca
    Olino, Luciana
    de Magalhaes, Ana Maria Mueller
    Tavares, Juliana Petri
    Magnago, Tania Solange Bosi de Souza
    Dal Pai, Daiane
    REVISTA LATINO-AMERICANA DE ENFERMAGEM, 2023, 31