Debenzylation and cyclization reaction of certain 1-aryl-5-tetra-O-benzoyl-β-D-glucopyranosyl-2-S-benzyl-2,4-isodithiobiurets:: Direct synthesis of 3-tetra-O-benzoyl-β-D-glucopyranosylimino-5-arylimino1,2,4-dithiazolidines and their antimicrobial activity

Several-3-tetra-O-benzoyi-beta-D-glucopyranosylimino-5-arylimino-1,2,4-dithiazolidines (3) have been synthesized by debenzylation and cyclization of 1-aryl-5-tetra-O-benzoyl-beta-D-glucopyranosyl-2-S-benzyl-2,4-isodithiobiurets by bromine in chloroform. The identities of these new N-glucosylated-1,2,4-dithiazolidines (3) have been established on the basis of usual chemical transformations and IR, NMR and mass spectral studies. The compounds were also screened for their antibacterial and antifungal activities against S. aureus, E coli, P. vulgaris, Bacillus, sp., Pseudomonas, Salmonella sp., A. niger and Fusarium.