Copper(I)-Catalyzed Thiolation of C-H Bonds for the Synthesis of Sulfenyl Pyrroles and Indoles

被引：17

作者：

Xu, Wei ^{[1
]}

Hei, Yu-Yuan ^{[1
]}

Song, Jian-Lan ^{[1
]}

Zhan, Xin-Chen ^{[1
]}

Zhang, Xing-Guo ^{[1
]}

Deng, Chen-Liang ^{[1
]}

机构：

[1] Wenzhou Univ, Coll Chem & Mat Engn, Wenzhou 325035, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2019年 / 51卷 / 02期

基金：

中国国家自然科学基金;

关键词：

copper(I) iodide; ligands; thiolation; pyrroles; indoles; CATALYZED SULFENYLATION; TERMINAL ALKYNES; CYANATION; DISULFIDES; ALLYLATION; ACTIVATION; INHIBITORS; ALCOHOLS; CLEAVAGE; LIGANDS;

D O I：

10.1055/s-0037-1610295

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and convenient copper(I)-catalyzed thiolation of C-H bonds of pyrroles and indoles is developed for the synthesis of sulfenyl pyrroles and indoles. Dual C-H thiolation reactions are observed for pyrroles. A wide range of pyrroles and indoles undergo the C-H thiolation smoothly with various disulfides and diselenides to generate the corresponding heteroaryl thioethers in moderate to excellent yields.

引用

页码：545 / 551

页数：7

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