Consensus Statement on Proton Therapy for Prostate Cancer

被引:20
作者
Bryant, Curtis M. [1 ]
Henderson, Randal H. [1 ]
Nichols, R. Charles [1 ]
Mendenhall, William M. [1 ]
Hoppe, Bradford S. [2 ]
Vargas, Carlos E. [3 ]
Daniels, Thomas B. [3 ]
Choo, C. Richard [4 ]
Parikh, Rahul R. [5 ]
Giap, Huan [6 ]
Slater, Jerry D. [7 ]
Vapiwala, Neha [8 ]
Barrett, William [9 ]
Nanda, Akash [10 ]
Mishra, Mark, V [11 ]
Choi, Seungtaek [12 ]
Liao, Jay J. [13 ]
Mendenhall, Nancy P. [1 ]
机构
[1] Univ Florida, Coll Med, Dept Radiat Oncol, Gainesville, FL 32206 USA
[2] Mayo Clin, Dept Radiat Oncol, Jacksonville, FL 32224 USA
[3] Mayo Clin, Dept Radiat Oncol, Phoenix, AZ USA
[4] Mayo Clin Rochester, Dept Radiat Oncol, Rochester, MN USA
[5] Rutgers Canc Inst New Jersey, Dept Radiat Oncol, New Brunswick, NJ USA
[6] Univ Miami, Sylvester Comprehens Canc Ctr, Dept Radiat Oncol, Miami, FL USA
[7] Loma Linda Univ, Dept Radiat Oncol, Loma Linda, CA 92350 USA
[8] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA
[9] Univ Cincinnati, Dept Radiat Oncol, Cincinnati, OH USA
[10] Orlando Hlth, Dept Radiat Oncol, Orlando, FL USA
[11] Univ Maryland, Sch Med, Dept Radiat Oncol, Baltimore, MD 21201 USA
[12] MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX USA
[13] Univ Washington, Med Ctr, Dept Radiat Oncol, Seattle, WA 98195 USA
关键词
prostate cancer; radiation therapy; proton therapy; particle therapy; INTENSITY-MODULATED RADIOTHERAPY; EXTERNAL-BEAM RADIOTHERAPY; PATIENT-REPORTED OUTCOMES; LONG-TERM OUTCOMES; QUALITY-OF-LIFE; RADIATION-THERAPY; 5-YEAR OUTCOMES; INTRAFRACTION MOTION; RANDOMIZED-TRIAL; TOXICITY;
D O I
10.14338/IJPT-20-00031.1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.
引用
收藏
页码:1 / 16
页数:16
相关论文
共 65 条
  • [61] Hypofractionated Versus Standard Fractionated Proton-beam Therapy for Low-risk Prostate Cancer Interim Results of a Randomized Trial PCG GU 002
    Vargas, Carlos E.
    Hartsell, William F.
    Dunn, Megan
    Keole, Sameer R.
    Doh, Lucius
    Eisenbeisz, Elaine
    Larson, Gary L.
    [J]. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2018, 41 (02): : 115 - 120
  • [62] Urinary symptoms following external beam radiotherapy of the prostate: Dose-symptom correlates with multiple-event and event-count models
    Yahya, Noorazrul
    Ebert, Martin A.
    Bulsara, Max
    House, Michael J.
    Kennedy, Angel
    Joseph, David J.
    Denham, James W.
    [J]. RADIOTHERAPY AND ONCOLOGY, 2015, 117 (02) : 277 - 282
  • [63] RADIATION-INDUCED CANCERS FROM MODERN RADIOTHERAPY TECHNIQUES: INTENSITY-MODULATED RADIOTHERAPY VERSUS PROTON THERAPY
    Yoon, Myonggeun
    Ahn, Sung Hwan
    Kim, Jinsung
    Shin, Dong Ho
    Park, Sung Yong
    Lee, Se Byeong
    Shin, Kyung Hwan
    Cho, Kwan Ho
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 77 (05): : 1477 - 1485
  • [64] What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation
    Zaorsky, Nicholas G.
    Palmer, Joshua D.
    Hurwitz, Mark D.
    Keith, Scott W.
    Dicker, Adam P.
    Den, Robert B.
    [J]. RADIOTHERAPY AND ONCOLOGY, 2015, 115 (03) : 295 - 300
  • [65] Zeitlin R, 2015, INT J PARTICLE THER, V2, P29