Consensus Statement on Proton Therapy for Prostate Cancer

被引:20
作者
Bryant, Curtis M. [1 ]
Henderson, Randal H. [1 ]
Nichols, R. Charles [1 ]
Mendenhall, William M. [1 ]
Hoppe, Bradford S. [2 ]
Vargas, Carlos E. [3 ]
Daniels, Thomas B. [3 ]
Choo, C. Richard [4 ]
Parikh, Rahul R. [5 ]
Giap, Huan [6 ]
Slater, Jerry D. [7 ]
Vapiwala, Neha [8 ]
Barrett, William [9 ]
Nanda, Akash [10 ]
Mishra, Mark, V [11 ]
Choi, Seungtaek [12 ]
Liao, Jay J. [13 ]
Mendenhall, Nancy P. [1 ]
机构
[1] Univ Florida, Coll Med, Dept Radiat Oncol, Gainesville, FL 32206 USA
[2] Mayo Clin, Dept Radiat Oncol, Jacksonville, FL 32224 USA
[3] Mayo Clin, Dept Radiat Oncol, Phoenix, AZ USA
[4] Mayo Clin Rochester, Dept Radiat Oncol, Rochester, MN USA
[5] Rutgers Canc Inst New Jersey, Dept Radiat Oncol, New Brunswick, NJ USA
[6] Univ Miami, Sylvester Comprehens Canc Ctr, Dept Radiat Oncol, Miami, FL USA
[7] Loma Linda Univ, Dept Radiat Oncol, Loma Linda, CA 92350 USA
[8] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA
[9] Univ Cincinnati, Dept Radiat Oncol, Cincinnati, OH USA
[10] Orlando Hlth, Dept Radiat Oncol, Orlando, FL USA
[11] Univ Maryland, Sch Med, Dept Radiat Oncol, Baltimore, MD 21201 USA
[12] MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX USA
[13] Univ Washington, Med Ctr, Dept Radiat Oncol, Seattle, WA 98195 USA
关键词
prostate cancer; radiation therapy; proton therapy; particle therapy; INTENSITY-MODULATED RADIOTHERAPY; EXTERNAL-BEAM RADIOTHERAPY; PATIENT-REPORTED OUTCOMES; LONG-TERM OUTCOMES; QUALITY-OF-LIFE; RADIATION-THERAPY; 5-YEAR OUTCOMES; INTRAFRACTION MOTION; RANDOMIZED-TRIAL; TOXICITY;
D O I
10.14338/IJPT-20-00031.1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.
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页码:1 / 16
页数:16
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