Novel chitosan-pectin composite membranes with enhanced strength, hydrophilicity and controllable disintegration

被引：71

作者：

Chen, Po-Hui ^{[1
]}

Kuo, Ting-Yun ^{[1
]}

Kuo, Jen-Yuan ^{[1
]}

Tseng, Yen-Po ^{[1
]}

Wang, Da-Ming ^{[1
]}

Lai, Juin-Yih ^{[2
]}

Hsieh, Hsyue-Jen ^{[1
]}

机构：

[1] Natl Taiwan Univ, Dept Chem Engn, Taipei 10617, Taiwan

[2] Chung Yuan Christian Univ, Res & Dev Ctr Membrane Technol, Tao Yuan 32083, Taiwan

来源：

CARBOHYDRATE POLYMERS | 2010年 / 82卷 / 04期

关键词：

Chitosan; Pectin; Polyelectrolyte complex (PEC); Ionic crosslinking; Disintegration; FILMS; ALGINATE; CALCIUM; MULTILAYER; SCAFFOLDS; BINDING; PROTEIN;

D O I：

10.1016/j.carbpol.2010.06.057

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Novel composite porous membranes made of basic and acidic polysaccharides (i.e. chitosan and pectin) were developed. Three types of chitosan/pectin composite membranes were fabricated: PEC-type (by polyelectrolyte complex (PEC) formation between chitosan and pectin); PEC/Ca-type (by PEC and calcium ion-mediated ionic crosslinking toward pectin); and PEC/covalent-type membranes (by PEC and EDC/NHS-mediated covalent bond). Tensile strengths (about fourfold that of pure chitosan membranes), hydrophilicity and water uptake capability of the composite membranes were significantly greater than membranes composed of chitosan or pectin only. Such composite membranes had faster disintegration rates which could be controlled by the content of pectin. Addition of calcium ions or EDC/NHS further increased the tensile strengths of the composite membranes (by about 1.5-fold) and also changed the profile of disintegration. Such chitosan/pectin composite membranes, due to their enhanced strength, hydrophilicity and controllable disintegration behavior, have potential as edible sponges or disintegrant carrying food or drug. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：1236 / 1242

页数：7

共 19 条

[11] Composite films from pectin and fish skin gelatin or soybean flour protein [J].

Liu, LinShu ;

Liu, Cheng-Kung ;

Fishman, Marshall L. ;

Hicks, Kevin B. .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2007, 55 (06) :2349-2355

[12] Chronic Ingestion of Apple Pectin Can Enhance the Absorption of Quercetin [J].

Nishijima, Tomohiko ;

Iwai, Kunihisa ;

Saito, Yasuo ;

Takida, Yoshiki ;

Matsue, Hajime .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (06) :2583-2587

[13] Preparation of rapidly disintegrating tablets containing itraconazole solid dispersions [J].

Oshima, Takao ;

Sonoda, Ryoichi ;

Ohkuma, Moriyuki ;

Sunada, Hisakazu .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2007, 55 (11) :1557-1562

[14] COMPOSITION FACTORS AFFECTING THE WATER-VAPOR PERMEABILITY AND TENSILE PROPERTIES OF HYDROPHILIC FILMS [J].

PARRIS, N ;

COFFIN, DR ;

JOUBRAN, RF ;

PESSEN, H .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1995, 43 (06) :1432-1435

[15] Polysaccharide-based artificial extracellular matrix: Preparation and characterization of three-dimensional, macroporous chitosan and chondroitin sulfate composite scaffolds [J].

Peng, CK ;

Yu, SH ;

Mi, FL ;

Shyu, SS .

JOURNAL OF APPLIED POLYMER SCIENCE, 2006, 99 (05) :2091-2100

[16]

REGINALD HW, 1991, CHEM TECHNOLOGY PECT

[17] Improvement of stability and cell adhesion properties of polyelectrolyte multilayer films by chemical cross-linking [J].

Richert, L ;

Boulmedais, F ;

Lavalle, P ;

Mutterer, J ;

Ferreux, E ;

Decher, G ;

Schaaf, P ;

Voegel, JC ;

Picart, C .

BIOMACROMOLECULES, 2004, 5 (02) :284-294

[18] CONDUCTOMETRIC METHOD FOR COLLOID TITRATIONS [J].

TOEI, K ;

KOHARA, T .

ANALYTICA CHIMICA ACTA, 1976, 83 (MAY) :59-65

[19] Collagen-chitosan polymer as a scaffold for the proliferation of human adipose tissue-derived stem cells [J].

Zhu, Yanxia ;

Liu, Tianqing ;

Song, Kedong ;

Jiang, Bo ;

Ma, Xuehu ;

Cui, Zhanfeng .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2009, 20 (03) :799-808

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