Synthesis and properties of a novel bridged nucleic acid with a P3′→N5′ phosphoramidate linkage, 5′-amino-2′,4′-BNA

被引：21

作者：

Obika, S ^{[1
]}

Nakagawa, O ^{[1
]}

Hiroto, A ^{[1
]}

Hari, Y ^{[1
]}

Imanishi, T ^{[1
]}

机构：

[1] Osaka Univ, Grad Sch Pharmaceut Sci, Osaka 5650871, Japan

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 17期

关键词：

D O I：

10.1039/b307290h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

5'-Amino-2', 4'-BNA, a novel analogue of BNA series compounds, was successfully synthesized, and its incorporated oligonucleotides showed potent duplex- and triplex-forming ability and resistance against snake venom phosphodiesterase.

引用

页码：2202 / 2203

页数：2

共 25 条

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