Adult zebrafish as a model organism for behavioural genetics

被引：255
作者：
Norton, William [1 ]
Bally-Cuif, Laure [1 ]
机构：
[1] CNRS, UPR 3294, Inst Neurobiol Albert Fessard, Zebrafish Neurogenet Grp,Lab Neurobiol & Dev NED, F-91198 Gif Sur Yvette, France
来源：
BMC NEUROSCIENCE | 2010年 / 11卷
关键词：
DANIO-RERIO; MEMORY CONSOLIDATION; MESSENGER-RNA; FISH; IDENTIFICATION; SYSTEM; GENES; SLEEP; TELENCEPHALON; CONSERVATION;
D O I：
10.1186/1471-2202-11-90
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Recent research has demonstrated the suitability of adult zebrafish to model some aspects of complex behaviour. Studies of reward behaviour, learning and memory, aggression, anxiety and sleep strongly suggest that conserved regulatory processes underlie behaviour in zebrafish and mammals. The isolation and molecular analysis of zebrafish behavioural mutants is now starting, allowing the identification of novel behavioural control genes. As a result of this, studies of adult zebrafish are now helping to uncover the genetic pathways and neural circuits that control vertebrate behaviour.
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页数：11
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