Small molecules as inhibitors of cyclin-dependent kinases

被引:168
|
作者
Huwe, A [1 ]
Mazitschek, R [1 ]
Giannis, A [1 ]
机构
[1] Univ Leipzig, Inst Organ Chem, D-04103 Leipzig, Germany
关键词
cell cycle; cyclins; drug design inhibitors; kinases;
D O I
10.1002/anie.200200540
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
引用
收藏
页码:2122 / 2138
页数:17
相关论文
共 50 条
  • [31] Discovery of potent and selective inhibitors of cyclin-dependent kinases
    Keertikar, Kerry M.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
  • [32] Cell cycle regulation by cyclin-dependent kinases and their inhibitors
    Barbacid, M
    EUROPEAN JOURNAL OF CANCER, 2002, 38 : S91 - S91
  • [33] 2-Aminoquinazoline inhibitors of cyclin-dependent kinases
    Bathini, Y
    Singh, I
    Harvey, PJ
    Keller, PR
    Singh, R
    Micetich, RG
    Fry, DW
    Dobrusin, EM
    Toogood, PL
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (17) : 3881 - 3885
  • [34] Inhibitors of Cyclin-Dependent Kinases: Types and Their Mechanism of Action
    Lukasik, Pawel
    Baranowska-Bosiacka, Irena
    Kulczycka, Katarzyna
    Gutowska, Izabela
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (06) : 1 - 23
  • [35] Small-molecule inhibitors of cyclin-dependent kinases: Molecular tools and potential therapeutics
    Walker, DH
    CYCLIN DEPENDENT KINASE (CDK) INHIBITORS, 1998, 227 : 149 - 165
  • [36] ATP-site directed inhibitors of cyclin-dependent kinases
    Gray, N
    Detivaud, L
    Doerig, C
    Meijer, L
    CURRENT MEDICINAL CHEMISTRY, 1999, 6 (09) : 859 - 875
  • [37] The discovery of cyclin-dependent kinases
    Nurse, Paul
    NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2024, 25 (10) : 763 - 763
  • [38] Structural bioinformatics study of cyclin-dependent kinases complexed with inhibitors
    Canduri, F
    da Silveira, NJF
    Camera, JC
    de Azevedo, WF
    ECLETICA QUIMICA, 2003, 28 (01): : 45 - 53
  • [39] Properties and potential applications of chemical inhibitors of cyclin-dependent kinases
    Meijer, L
    Leclerc, S
    Leost, M
    PHARMACOLOGY & THERAPEUTICS, 1999, 82 (2-3) : 279 - 284
  • [40] Mammalian cyclin-dependent kinases
    Malumbres, M
    Barbacid, M
    TRENDS IN BIOCHEMICAL SCIENCES, 2005, 30 (11) : 630 - 641