Synthesis of 3-Aryl-2-pyrones by Palladium-Catalyzed Cross-Coupling of Aryl Iodides with Cyclic Vinyldiazo Ester

被引：13

作者：

Huang, Jun ^{[1
,2
]}

Li, Linyong ^{[1
]}

Chen, Haoguo ^{[1
]}

Xiao, Tiebo ^{[1
]}

He, Yuwei ^{[1
]}

Zhou, Lei ^{[1
]}

机构：

[1] Sun Yat Sen Univ, Sch Chem, 135 Xingang West Rd, Guangzhou 510275, Guangdong, Peoples R China

[2] Guangxi Teachers Educ Univ, Coll Chem & Mat Sci, 175 Mingxiu East Rd, Nanning 530001, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 17期

关键词：

CARBENE MIGRATORY INSERTION; DIELS-ALDER REACTION; N-TOSYLHYDRAZONES; CARBON NUCLEOPHILES; DIAZO-COMPOUNDS; METAL CARBENE; 3,5-DIBROMO-2-PYRONE; 2-PYRONES; 2H-PYRAN-2-ONES; ORGANOSTANNANES;

D O I：

10.1021/acs.joc.7b01470

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium-catalyzed cross-coupling reaction of aryl iodides with cyclic vinyldiazo ester was developed. The reaction provides various 3-aryl-2-pyrones in good yields with high functional group tolerance. The synthetic application of the resulting 3-aryl-2-pyrones as the diene component in a Diels-Alder reaction was also described.

引用

页码：9204 / 9209

页数：6

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