A Glutamate Pathway to Faster-Acting Antidepressants?

被引：33

作者：

Cryan, John F. ^{[1
]}

O'Leary, Olivia F. ^{[1
]}

机构：

[1] Natl Univ Ireland Univ Coll Cork, Sch Pharm, Dept Pharmacol & Therapeut, Alimentary Pharmabiot Ctr, Cork, Ireland

来源：

SCIENCE | 2010年 / 329卷 / 5994期

关键词：

D-ASPARTATE ANTAGONIST; DEPRESSION; RECEPTORS; RAPAMYCIN; KETAMINE; TRIAL;

D O I：

10.1126/science.1194313

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Activation of mTOR, a ubiquitous protein, in the prefrontal cortex could be a key goal of new drugs.

引用

页码：913 / 914

页数：2

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