In this article we introduce an insect (blowfly Calliphora vicina) olfactory biosensor. This biosensor has proved sensitive to the vapour of biogenic amines, and especially to 1,4-diaminobutane, According to our electrophysiological experiments the blowfly olfactory biosensor was sensitive to the 1,4-diaminobutane odour (<1 ng in stimulus air pulse), but less sensitive to 1,3-diaminopropane, 1,5-diaminopentane, 1,6-diaminohexane, 1,7-diaminoheptane and ammoniac odour (<100 mu g on stimulus cartridge). Based on time to voltage conversion and visual inspection we have determined the action potential rate as the response value. Also according to our behavioural tests the odour of 1,4-diaminobutane attracted clearly the blowflies.