The Brix domain protein family - a key to the ribosomal biogenesis pathway?

被引：41

作者：

Eisenhaber, F

Wechselberger, C

Kreil, G

机构：

[1] Res Inst Mol Pathol, A-1030 Vienna, Austria

[2] NCI, Tumor Growth Factor Sect, NIH, Bethesda, MD 20892 USA

[3] Austrian Acad Sci, Inst Mol Biol, A-5020 Salzburg, Austria

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2001年 / 26卷 / 06期

关键词：

D O I：

10.1016/S0968-0004(01)01851-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Six (one archaean and five eukaryotic) protein families have similar domain architecture that includes a central globular Brix domain, and optional N- and obligatory C-terminal segments, both with charged low-complexity regions. Biological data for some proteins in this superfamily suggest a role in ribosome biogenesis and rRNA binding.

引用

收藏

页码：345 / 347

页数：3

相关论文

共 14 条

[1] Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].

Altschul, SF ;

Madden, TL ;

Schaffer, AA ;

Zhang, JH ;

Zhang, Z ;

Miller, W ;

Lipman, DJ .

NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402

[2]

Cuff JA, 2000, PROTEINS, V40, P502, DOI 10.1002/1097-0134(20000815)40:3<502::AID-PROT170>3.0.CO

[3]

2-Q

[4] Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library [J].

Ding, DQ ;

Tomita, Y ;

Yamamoto, A ;

Chikashige, Y ;

Haraguchi, T ;

Hiraoka, Y .

GENES TO CELLS, 2000, 5 (03) :169-190

[5] Functional genomic analysis of cell division in C-elegans using RNAi of genes on chromosome III [J].

Gönczy, P ;

Echeverri, C ;

Oegema, K ;

Coulson, A ;

Jones, SJM ;

Copley, RR ;

Duperon, J ;

Oegema, J ;

Brehm, M ;

Cassin, E ;

Hannak, E ;

Kirkham, M ;

Pichler, S ;

Flohrs, K ;

Goessen, A ;

Leidel, S ;

Alleaume, AM ;

Martin, C ;

Özlü, N ;

Bork, P ;

Hyman, AA .

NATURE, 2000, 408 (6810) :331-336

[6]

Kim J, 1998, GENETICS, V149, P795

[7]

Kressler D, 1999, MOL CELL BIOL, V19, P7897

[8]

Lee SJ, 1999, MOL CELL BIOL, V19, P5441

[9] The archaeal homolog of the Imp4 protein, a eukaryotic U3 snoRNP component [J].

Mayer, C ;

Suck, D ;

Poch, O .

TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (03) :143-144

[10] Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth [J].

Migeon, JC ;

Garfinkel, MS ;

Edgar, BA .

MOLECULAR BIOLOGY OF THE CELL, 1999, 10 (06) :1733-1744