First halogen dance reaction on oxazoles. Synthesis of 4,5-disubstituted 2-phenyloxazoles

被引：16

作者：

Stanetty, P ^{[1
]}

Spina, M ^{[1
]}

Mihovilovic, MD ^{[1
]}

机构：

[1] Vienna Tech Univ, Inst Appl Synth Chem, A-1060 Vienna, Austria

来源：

SYNLETT | 2005年 / 09期

关键词：

halogen dance; metalation; lithiation; oxazole;

D O I：

10.1055/s-2005-868523

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The halogen dance reaction was investigated on the oxazole system for the first time. Various 5-substituted 4-bromo-2-phenyloxazole derivatives are accessible via this convenient methodology.

引用

页码：1433 / 1434

页数：2

共 32 条

[1]

[Anonymous], 1994, PROG HETEROCYCL CHEM

[2]

Arzel E, 1999, HETEROCYCLES, V50, P215

[3] First total synthesis of cryptomisrine [J].

Arzel, E ;

Rocca, P ;

Marsais, F ;

Godard, A ;

Quéguiner, G .

TETRAHEDRON, 1999, 55 (41) :12149-12156

[4] First halogen-dance reaction in quinoline series:: application to a new synthesis of quindoline. [J].

Arzel, E ;

Rocca, P ;

Marsais, F ;

Godard, A ;

Quéguiner, G .

TETRAHEDRON LETTERS, 1998, 39 (36) :6465-6466

[5]

COCHENNEC C, 1995, SYNTHESIS-STUTTGART, P321

[6]

DEBIE DA, 1968, TETRAHEDRON LETT, P3905

[7]

DEBIE DA, 1969, RECL TRAV CHIM PAY-B, V88, P1246

[8]

DEBIE DA, 1973, RECL TRAV CHIM PAY B, V92, P245

[9]

Frohlich J, 1996, B SOC CHIM BELG, V105, P615

[10] Synthesis of trisubstituted thiophenes via a halogen dance reaction at 2-bromo-5-methylthiophene [J].

Frohlich, J ;

Hametner, C ;

Kalt, W .

MONATSHEFTE FUR CHEMIE, 1996, 127 (03) :325-330

← 1 2 3 4 →