Re-analysis of data and its integration

被引：6

作者：

Jensen, LJ ^{[1
]}

Steinmetz, LM ^{[1
]}

机构：

[1] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

FEBS LETTERS | 2005年 / 579卷 / 08期

关键词：

benchmarking; data integration; network analysis; gene expression; deletion phenotype;

D O I：

10.1016/j.febslet.2005.02.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

To understand a biological process it is clear that a single approach will not be sufficient, just like a single measurement on a protein - such as its expression level - does not describe protein function. Using reference sets of proteins as benchmarks different approaches can be scaled and integrated. Here, we demonstrate the power of data re-analysis and integration by applying it in a case study to data from deletion phenotype screens and mRNA expression profiling. (c) 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

收藏

页码：1802 / 1807

页数：6

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