Paving the Path toward Porcine Organs for Transplantation

被引：24
作者：
Denner, Joachim [1 ]
机构：
[1] Robert Koch Inst, Berlin, Germany
来源：
NEW ENGLAND JOURNAL OF MEDICINE | 2017年 / 377卷 / 19期
关键词：
TRIAL;
D O I：
10.1056/NEJMcibr1710853
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：1891 / 1893
页数：3
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共 5 条
[1]   No PERV transmission during a clinical trial of pig islet cell transplantation [J].
Morozov, Vladimir A. ;
Wynyard, Shaun ;
Matsumoto, Shinichi ;
Abalovich, Adrian ;
Denner, Joachim ;
Elliott, Robert .
VIRUS RESEARCH, 2017, 227 :34-40
[2]   Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9 [J].
Niu, Dong ;
Wei, Hong-Jiang ;
Lin, Lin ;
George, Haydy ;
Wang, Tao ;
Lee, Hsiu ;
Zhao, Hong-Ye ;
Wang, Yong ;
Kan, Yinan ;
Shrock, Ellen ;
Lesha, Emal ;
Wang, Gang ;
Luo, Yonglun ;
Qing, Yubo ;
Jiao, Deling ;
Zhao, Heng ;
Zhou, Xiaoyang ;
Wang, Shouqi ;
Wei, Hong ;
Gueell, Marc ;
Church, George M. ;
Yang, Luhan .
SCIENCE, 2017, 357 (6357) :1303-1307
[3]   Cytotoxic Effects during Knock Out of Multiple Porcine Endogenous Retrovirus (PERV) Sequences in the Pig Genome by Zinc Finger Nucleases (ZFN) [J].
Semaan, Marwan ;
Ivanusic, Daniel ;
Denner, Joachim .
PLOS ONE, 2015, 10 (04)
[4]   Microbiological safety of the first clinical pig islet xenotransplantation trial in New Zealand [J].
Wynyard, Shaun ;
Nathu, Divya ;
Garkavenko, Olga ;
Denner, Joachim ;
Elliott, Robert .
XENOTRANSPLANTATION, 2014, 21 (04) :309-323
[5]   Genome-wide inactivation of porcine endogenous retroviruses (PERVs) [J].
Yang, Luhan ;
Gueell, Marc ;
Niu, Dong ;
George, Haydy ;
Lesha, Emal ;
Grishin, Dennis ;
Aach, John ;
Shrock, Ellen ;
Xu, Weihong ;
Poci, Juergen ;
Cortazio, Rebeca ;
Wilkinson, Robert A. ;
Fishman, Jay A. ;
Church, George .
SCIENCE, 2015, 350 (6264) :1101-1104
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