A piece-wise harmonic Langevin model of EEG dynamics: Theory and application to EEG seizure detection

被引:0
作者
Hsu, M [1 ]
Hsu, D [1 ]
机构
[1] Univ Wisconsin Hosp & Clin, Dept Neurol, Madison, WI 53792 USA
关键词
EEG; seizure detection; potential energy; particle dynamics;
D O I
10.1016/j.neucom.2004.11.003
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
Electroencephalogram (EEG) dynamics results from the motion of charged particles in the brain. By invoking the laws of classical physics, we show that EEG dynamics obeys, at short enough times, a piece-wise quadratic Langevin equation characterized by an effective mass matrix, a piece-wise quadratic potential energy surface, a friction and random force matrix. In analyzing a sample seizure, we find with seizure onset a marked increase in the frequency of encounters with inflection points on the potential energy surface. (c) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码:469 / 474
页数:6
相关论文
共 13 条
  • [1] Arbib M., 2003, HDB BRAIN THEORY NEU
  • [2] Berne B. J., 1970, Advances in chemical physics vol. 18, P63, DOI 10.1002/9780470143636.ch3
  • [3] THE SHORT-TIME DYNAMICS OF MOLECULAR LIQUIDS - INSTANTANEOUS-NORMAL-MODE THEORY
    BUCHNER, M
    LADANYI, BM
    STRATT, RM
    [J]. JOURNAL OF CHEMICAL PHYSICS, 1992, 97 (11) : 8522 - 8535
  • [4] De Schutter E, 1999, REV NEUROSCIENCE, V10, P233
  • [5] IASEMIDIS L D, 1990, Brain Topography, V2, P187, DOI 10.1007/BF01140588
  • [6] Instantaneous normal mode approach to liquid state dynamics
    Keyes, T
    [J]. JOURNAL OF PHYSICAL CHEMISTRY A, 1997, 101 (16) : 2921 - 2930
  • [7] Wavelet based automatic seizure detection in intracerebral electroencephalogram
    Khan, YU
    Gotman, J
    [J]. CLINICAL NEUROPHYSIOLOGY, 2003, 114 (05) : 898 - 908
  • [8] Characterizing neurodynamic changes before seizures
    Le Van Quyen, M
    Martinerie, J
    Navarro, V
    Baulac, M
    Varela, FJ
    [J]. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2001, 18 (03) : 191 - 208
  • [9] Nonlinear EEG analysis in epilepsy: Its possible use for interictal focus localization, seizure anticipation, and prevention
    Lehnertz, K
    Andrzejak, RG
    Arnhold, J
    Kreuz, T
    Mormann, F
    Rieke, C
    Widman, G
    Elger, CE
    [J]. JOURNAL OF CLINICAL NEUROPHYSIOLOGY, 2001, 18 (03) : 209 - 222
  • [10] Seizure prediction and the preseizure period
    Litt, B
    Lehnertz, K
    [J]. CURRENT OPINION IN NEUROLOGY, 2002, 15 (02) : 173 - 177