Cobalt-Catalyzed, Hydroxyl-Assisted C-H Bond Functionalization: Access to Diversely Substituted Polycyclic Pyrans

被引：26
作者：
Dutta, Pratip K. [1 ]
Ravva, Mahesh Kumar [2 ]
Sen, Subhabrata [1 ,2 ]
机构：
[1] Shiv Nadar Univ, Sch Nat Sci, Dept Chem, Gautam Budh Nagar 201314, Uttar Pradesh, India
[2] SRM Univ AP, Dept Chem, Amaravati 522020, Andhra Pradesh, India
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 84卷 / 03期
关键词：
ACTIVATION; ANNULATION; ALKYNES; DERIVATIVES; PALLADIUM; CLEAVAGE; ARYLATION; COPPER; ACIDS;
D O I：
10.1021/acs.joc.8b02446
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Highly efficient oxidative annulation of alkynes furnished diversely substituted pyran[2,3,4-de] chromene-2-one derivatives and related polycycles in moderate to high yield. The reaction is catalyzed by nontoxic, air-stable, and inexpensive Cp*Co(CO)I-2 catalyst. The hydroxyl moiety at the substrate acts as the directing group for the C-H bond activation.
引用
收藏
页码：1176 / 1184
页数：9
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