Microwave assisted synthesis of ethyl 2,4-disubstituted thiazole-5-acetates for their antioxidant activity

被引：0
|
作者：
Mohan, S [1 ]
Attimarad, M [1 ]
机构：
[1] Al Ameen Coll Pharm, Dept Pharmaceut Chem, Bangalore 560027, Karnataka, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2005年 / 17卷 / 02期
关键词：
synthesis; substituted thiazole; microwave; antioxidant activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Synthesis of ethyl 3-aroylpropionates (3-4) has been conducted under microwave irradiation in open vessels and then brominated to ethyl 3-bromo-3-aroylpropionate (5-6). Ethyl 2,4-disubstituted thiazole-5-acetates (8a-s) have been synthesized by condensing thiourea/(un)substituted phenylthiourea (7) with bromo ester (5-6) under microwave irradiation using ethanol as the microwave energy transfer agent. The synthesized compounds have been tested in-vitro for their antioxidant activity.
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页码：991 / 995
页数：5
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