8-chloro-5-(4-chlorophenyl)-5H-indeno-[1,2-d]pyrimidine

被引:2
作者
Caruso, F
Rossi, M
机构
[1] CNR, Ist Strutturist Chim, I-00016 Monterotondo, Italy
[2] Vassar Coll, Dept Chem, Poughkeepsie, NY 12604 USA
关键词
D O I
10.1107/S0108270198000572
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The title compound, C17H10Cl2N2, crystallizes with two independent molecules in the asymmetric unit, with little conformational difference between them. The molecules have two planar components and the angle between the two planes is 95.5 degrees in molecule I and 97.3 degrees in molecule II. The crystal structure exhibits only van der Waals interactions, The three-dimensional structure and folding of the two independent molecules in the asymmetric unit are reminiscent of other P450 aromatase inhibitors.
引用
收藏
页码:842 / 844
页数:3
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