Drug encapsulation within self-assembled microglobules formed by thermoresponsive supramolecules

被引：22

作者：

Betancourt, Jose E. ^{[1
]}

Subramani, Chandramouleeswaran ^{[2
]}

Serrano-Velez, Jose L. ^{[3
]}

Rosa-Molinar, Eduardo ^{[3
]}

Rotello, Vincent M. ^{[2
]}

Rivera, Jose M. ^{[1
]}

机构：

[1] Univ Puerto Rico, Dept Chem, San Juan, PR 00931 USA

[2] Univ Massachusetts, Dept Chem, Amherst, MA 01003 USA

[3] Univ Puerto Rico, Dept Biol, San Juan, PR 00931 USA

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 45期

基金：

美国国家科学基金会;

关键词：

PH-RESPONSIVE MICELLES; 2'-DEOXYGUANOSINE DERIVATIVES; DELIVERY; NANOCARRIERS; DOXORUBICIN; POLYMERS; COMPLEX;

D O I：

10.1039/c0cc04063k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An 8-(phenyl)-2'-deoxyguanosine derivative self-assembles in aqueous media into discrete hexadecamers that further self-assemble above 32 degrees C into microglobules that encapsulate the drug doxorubicin.

引用

页码：8537 / 8539

页数：3

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