Carbon nanotube based biosensors

被引:46
作者
Atashbar, MZ [1 ]
Bejcek, B [1 ]
Singamaneni, S [1 ]
Santucci, S [1 ]
机构
[1] Western Michigan Univ, Dept Elect & Comp Engn, Kalamazoo, MI 49008 USA
来源
PROCEEDINGS OF THE IEEE SENSORS 2004, VOLS 1-3 | 2004年
关键词
single walled carbon nanotubes; biomolecule; atomic force microscopy;
D O I
10.1109/ICSENS.2004.1426354
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In this paper we describe a single wall carbon nanotube (SWNT) based biological sensor for the detection of bio molecules like Streptavidin and IgG. SWNT have been employed for two types of sensing mechanisms. Firstly, the changes in the electrical conductance of the carbon nanotube matrix on non covalent binding of the biomolecules to the side walls of the carbon nanotube and secondly, quantification of mass uptake of the matrix on biomolecule incubation are presented Both sensing mechanisms exhibited consistent and highly sensitive responses. Biomolecular immobilization on the carbon nanotube surface was monitored by Atomic Force Microscopy.
引用
收藏
页码:1048 / 1051
页数:4
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