Critical flicker frequency in migraine. A controlled study in patients without prophylactic therapy

被引:20
作者
Kowacs, PA [1 ]
Piovesan, EJ [1 ]
Werneck, LC [1 ]
Fameli, H [1 ]
Zani, AC [1 ]
da Silva, HP [1 ]
机构
[1] Univ Fed Parana, Hosp Clin, Dept Internal Med, Neurol Div,Headache Unit, BR-80060900 Curitiba, Parana, Brazil
关键词
critical flicker frequency; flicker frequency threshold; migraine; migraine mechanisms; visual system;
D O I
10.1111/j.1468-2982.2004.00861.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The critical flicker frequencies (CFF) of individuals with migraine with and without aura were determined and compared to those of normal controls. Twenty-six migraine patients, 12 with aura and 14 without aura and 30 healthy controls were included. Migraineurs were tested during a migraine-free period, through both the continuous flicker method (CFM) and the forced choice method (FCM). Migraineurs presented a mean flickering fusion threshold lower than healthy controls with the CFM (40.45 vs. 44.33, respectively; P = 0.019) and with the FCM (34.16 Hz vs. 38.5 Hz, respectively, P = 0.019). Both groups of migraineurs had significantly lower thresholds as compared to controls, migraineurs with aura presenting the lowest thresholds for the fusion of flickering (P = 0.008 and P = 0.0001 with the CFM and the FCM, respectively). Results confirmed and extended previous observations of abnormal flicker fusion thresholds in migraineurs. We hypothesize that this finding might be related to a shorter cortical stimulation silent period.
引用
收藏
页码:339 / 343
页数:5
相关论文
共 21 条
[1]   The cortical silent period is shortened in migraine with aura [J].
Aurora, SK ;
Al-Sayeed, F ;
Welch, KMA .
CEPHALALGIA, 1999, 19 (08) :708-712
[2]   Functional MRI-BOLD of visually triggered headache in patients with migraine [J].
Cao, Y ;
Welch, KMA ;
Aurora, S ;
Vikingstad, EM .
ARCHIVES OF NEUROLOGY, 1999, 56 (05) :548-554
[3]   Functional MRI-BOLD of brainstem structures during visually triggered migraine [J].
Cao, Y ;
Aurora, SK ;
Nagesh, V ;
Patel, SC ;
Welch, KMA .
NEUROLOGY, 2002, 59 (01) :72-78
[4]   TELEVISION + EPILEPSY [J].
CHARLTON, MH ;
HOEFER, PFA .
ARCHIVES OF NEUROLOGY, 1964, 11 (03) :239-&
[5]   THRESHOLDS FOR DETECTION OF A TARGET AGAINST A BACKGROUND GRATING SUGGEST VISUAL DYSFUNCTION IN MIGRAINE WITH AURA BUT NOT MIGRAINE WITHOUT AURA [J].
CHRONICLE, EP ;
WILKINS, AJ ;
COLESTON, DM .
CEPHALALGIA, 1995, 15 (02) :117-122
[6]   Visual system dysfunction in migraine: A review of clinical and psychophysical findings [J].
Chronicle, EP ;
Mulleners, WM .
CEPHALALGIA, 1996, 16 (08) :525-535
[7]   RESPONSES TO TEMPORAL VISUAL-STIMULI IN MIGRAINE - THE CRITICAL FLICKER FUSION TEST [J].
COLESTON, DM ;
KENNARD, C .
CEPHALALGIA, 1995, 15 (05) :396-398
[8]   PRECORTICAL DYSFUNCTION OF SPATIAL AND TEMPORAL VISUAL PROCESSING IN MIGRAINE [J].
COLESTON, DM ;
CHRONICLE, E ;
RUDDOCK, KH ;
KENNARD, C .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1994, 57 (10) :1208-1211
[9]  
Glassner Andrew S, 1995, Principles of Digital Image Synthesis
[10]   Drug therapy: Migraine - Current understanding and treatment. [J].
Goadsby, PJ ;
Lipton, RB ;
Ferrari, MD .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (04) :257-270