Surface markers: An identity card of endothelial cells

被引:32
作者
Ribatti, Domenico [1 ]
Tamma, Roberto [1 ]
Ruggieri, Simona [1 ]
Annese, Tiziana [1 ]
Crivellato, Enrico [2 ]
机构
[1] Univ Bari, Dept Basic Med Sci Neurosci & Sensory Organs, Med Sch, Policlin Piazza G Cesare 11, I-70124 Bari, Italy
[2] Univ Udine, Sect Human Anat, Dept Med, Udine, Italy
关键词
endothelial precursor cells; endothelium; heterogeneity; surface marker; tumor; vascular system; ANGIOTENSIN-CONVERTING ENZYME; TARGETED DRUG-DELIVERY; VON-WILLEBRAND-FACTOR; HEMATOPOIETIC STEM; LYMPHATIC VESSELS; ENDOGLIN CD105; GROWTH-FACTOR; BIOCHEMICAL-CHARACTERIZATION; FUNCTIONAL-CHARACTERIZATION; DIFFERENTIAL EXPRESSION;
D O I
10.1111/micc.12587
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
All endothelial cells have the common characteristic that they line the vessels of the blood circulatory system. However, endothelial cells display a large degree of heterogeneity in the function of their location in the vascular tree. In this article, we have summarized the expression patterns of a number of well-accepted endothelial surface markers present in normal microvascular endothelial cells, arterial and venous endothelial cells, lymphatic endothelial cells, tumor endothelial cells, and endothelial precursor cells.
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页数:8
相关论文
共 99 条
[1]   Roles of ephrinB ligands and EphB receptors in cardiovascular development: demarcation of arterial/venous domains, vascular morphogenesis, and sprouting angiogenesis [J].
Adams, RH ;
Wilkinson, GA ;
Weiss, C ;
Diella, F ;
Gale, NW ;
Deutsch, U ;
Risau, W ;
Klein, R .
GENES & DEVELOPMENT, 1999, 13 (03) :295-306
[2]   Mechanisms of endothelial cell heterogeneity in health and disease [J].
Aird, WC .
CIRCULATION RESEARCH, 2006, 98 (02) :159-162
[3]  
Aird WC, 2011, COLD SPRING HARB PER, V2, pa006429
[4]   Phenotypic heterogeneity of the endothelium II. Representative vascular beds [J].
Aird, William C. .
CIRCULATION RESEARCH, 2007, 100 (02) :174-190
[5]   Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model [J].
Arap, W ;
Pasqualini, R ;
Ruoslahti, E .
SCIENCE, 1998, 279 (5349) :377-380
[6]   Environmental Specification of Pluripotent Stem Cell Derived Endothelial Cells Toward Arterial and Venous Subtypes [J].
Arora, Seep ;
Yim, Evelyn K. F. ;
Toh, Yi-Chin .
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2019, 7
[7]   Isolation of putative progenitor endothelial cells for angiogenesis [J].
Asahara, T ;
Murohara, T ;
Sullivan, A ;
Silver, M ;
vanderZee, R ;
Li, T ;
Witzenbichler, B ;
Schatteman, G ;
Isner, JM .
SCIENCE, 1997, 275 (5302) :964-967
[8]   EXPRESSION OF ORGAN-SPECIFIC ANTIGENS ON CAPILLARY ENDOTHELIAL-CELLS [J].
AUERBACH, R ;
ALBY, L ;
MORRISSEY, LW ;
TU, M ;
JOSEPH, J .
MICROVASCULAR RESEARCH, 1985, 29 (03) :401-411
[9]  
Auerbach R, 1992, ENDOTHELIAL CELL DYS, P427
[10]   LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan [J].
Banerji, S ;
Ni, J ;
Wang, SX ;
Clasper, S ;
Su, J ;
Tammi, R ;
Jones, M ;
Jackson, DG .
JOURNAL OF CELL BIOLOGY, 1999, 144 (04) :789-801