Tuning the electronic properties of dppz-ligands and their palladium(II) complexes

被引：36

作者：

Butsch, Katharina ^{[1
]}

Gust, Ronald ^{[2
]}

Klein, Axel ^{[1
]}

Ott, Ingo ^{[3
]}

Romanski, Marco ^{[1
]}

机构：

[1] Univ Cologne, Inst Anorgan Chem, D-50969 Cologne, Germany

[2] Free Univ Berlin, Inst Pharm Pharmazeut Chem, D-14195 Berlin, Germany

[3] Tech Univ Carolo Wilhelmina Braunschweig, Inst Pharmaceut Chem, D-38106 Braunschweig, Germany

来源：

DALTON TRANSACTIONS | 2010年 / 39卷 / 18期

关键词：

MOLECULAR LIGHT SWITCH; DNA-BINDING PROPERTIES; DIPYRIDOPHENAZINE COMPLEXES; POLYPYRIDYL COMPLEXES; RESONANCE RAMAN; CELLULAR UPTAKE; PLATINUM(II) COMPLEXES; RUTHENIUM(II) COMPLEX; METAL-COMPLEXES; EXCITED-STATES;

D O I：

10.1039/b926233d

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

New organometallic palladium complexes of the general type [(RR'dppz)Pd(Me)L](n+) (RR'dppz = derivatives of dipyrido[3,2-a:2',3'-c]phenazine with RR' = 11-Cl, 11,12-Cl-2, 11-CF3, 11-NO2, 11-NH2; L = Cl, 1-methyluracilate (n = 0), pyridine, cytosine, caffeine, or 1-methylcytosine, (all n = 1) were characterised and studied in detail by electrochemical and spectroscopic (NMR, UV/Vis-absorption and emission) methods. EPR spectroscopy and density functional calculations reveal markedly tuneable lowest unoccupied molecular orbitals (LUMO) located at the dppz ligands. Cytotoxicity experiments on HT-29 colon carcinoma and MCF-7 breast cancer cell lines show promising activities for selected compounds.

引用

页码：4331 / 4340

页数：10

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