DNA Origami Gatekeepers for Solid-State Nanopores

被引:161
作者
Wei, Ruoshan [1 ]
Martin, Thomas G. [2 ,3 ]
Rant, Ulrich [1 ]
Dietz, Hendrik [2 ,3 ]
机构
[1] Tech Univ Munich, Walter Schottky Inst, D-85748 Garching, Germany
[2] Tech Univ Munich, Ctr Integrated Prot Sci Munchen, D-85748 Garching, Germany
[3] Tech Univ Munich, Inst Adv Study, Dept Phys, D-85748 Garching, Germany
基金
欧洲研究理事会;
关键词
DNA self-assembly; DNA structures; nanopores; nanotechnology; single-molecule studies; NANOSCALE SHAPES; FOLDING DNA; PROTEIN; PORE; MOLECULES; ANALYTES; COMPLEX; DESIGN;
D O I
10.1002/anie.201200688
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
DNA has it covered: DNA origami gatekeeper nanoplates convert nanopores in solid-state membranes into versatile devices for label-free macromolecular sensing applications. The custom apertures in the nanoplates can be chemically addressed for sequence-specific detection of DNA. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:4864 / 4867
页数:4
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