Use of the BrainLAB exactrac X-ray 6D system in image-guided radiotherapy

被引:169
作者
Jin, Jian-Yue
Yin, Fang-Fang
Tenn, Stephen E.
Medin, Paul M.
Solberg, Timothy D.
机构
[1] Henry Ford Hlth Syst, Dept Radiat Oncol, Detroit, MI USA
[2] Duke Univ, Med Ctr, Dept Radiat Oncol, Durham, NC USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiat Oncol, Los Angeles, CA 90095 USA
[4] Univ Nebraska, Nebraska Med Ctr, Dept Radiat Oncol, Omaha, NE 68182 USA
关键词
image-guided radiation therapy; X-ray guidance; image fusion; respiratory gating;
D O I
10.1016/j.meddos.2008.02.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The ExacTrac X-Ray 6D image-guided radiotherapy (IGRT) system will be described and its performance evaluated. The system is mainly an integration of 2 subsystems: (1) an infrared (IR)-based optical positioning system (ExacTrac) and (2) a radiographic kV x-ray imaging system (X-Ray 6D). The infrared system consists of 2 IR cameras, which are used to monitor reflective body markers placed on the patient's skin to assist in patient initial setup, and an IR reflective reference star, which is attached to the treatment couch and can assist in couch movement with spatial resolution to better than 0.3 mm. The radiographic kV devices consist of 2 oblique x-ray imagers to obtain high-quality radiographs for patient position verification and adjustment. The position verification is made by fusing the radiographs with the simulation CT images using either 3 degree-of-freedom (31)) or 6 degree-of-freedom (6D) fusion algorithms. The position adjustment is performed using the infrared system according to the verification results. The reliability of the fusion algorithm will be described based on phantom and patient studies. The results indicated that the 6D fusion method is better compared to the 3D method if there are rotational deviations between the simulation and setup positions. Recently, the system has been augmented with the capabilities for image-guided positioning of targets in motion due to respiration and for gated treatment of those targets. The infrared markers provide a respiratory signal for tracking and gating of the treatment beam, with the x-ray system providing periodic confirmation of patient position relative to the gating window throughout the duration of the gated delivery. 0 2008 American Association of Medical Dosimetrists.
引用
收藏
页码:124 / 134
页数:11
相关论文
共 45 条
[1]   A feasibility study on the prediction of tumour location in the lung from skin motion [J].
Ahn, S ;
Yi, B ;
Suh, Y ;
Kim, J ;
Lee, S ;
Shin, S ;
Shin, S ;
Choi, E .
BRITISH JOURNAL OF RADIOLOGY, 2004, 77 (919) :588-596
[2]   Real-time three-dimensional motion analysis for patient positioning verification [J].
Baroni, G ;
Ferrigno, G ;
Orecchia, R ;
Pedotti, A .
RADIOTHERAPY AND ONCOLOGY, 2000, 54 (01) :21-27
[3]   Performing daily prostate targeting with a standard V-EPID and an automated radio-opaque marker detection algorithm [J].
Beaulieu, L ;
Girouard, LM ;
Aubin, S ;
Aubry, JF ;
Brouard, L ;
Roy-Lacroix, L ;
Dumont, J ;
Tremblay, D ;
Laverdière, J ;
Vigneault, E .
RADIOTHERAPY AND ONCOLOGY, 2004, 73 (01) :61-64
[4]   Residual motion of lung tumours in gated radiotherapy with external respiratory surrogates [J].
Berbeco, RI ;
Nishioka, S ;
Shirato, H ;
Chen, GTY ;
Jiang, SB .
PHYSICS IN MEDICINE AND BIOLOGY, 2005, 50 (16) :3655-3667
[5]  
BERBECO RI, 2004, P 14 INT C COMP US R
[6]  
Cheng Chee-Wai, 2003, Am J Clin Oncol, V26, pe28, DOI 10.1097/00000421-200306000-00027
[7]   Evaluation of mechanical precision and alignment uncertainties for an integrated CT/LINAC system [J].
Court, L ;
Rosen, I ;
Mohan, R ;
Dong, L .
MEDICAL PHYSICS, 2003, 30 (06) :1198-1210
[8]   Spinal lesions treated with Novalis shaped beam intensity-modulated radiosurgery and stereotactic radiotherapy [J].
De Salles, AAF ;
Pedroso, AG ;
Medin, P ;
Agazaryan, N ;
Solberg, T ;
Cabatan-Awang, C ;
Espinosa, DM ;
Ford, J ;
Selch, MT .
JOURNAL OF NEUROSURGERY, 2004, 101 (03) :435-440
[9]   Real-time 3D surface-image-guided beam setup in radiotherapy of breast cancer [J].
Djajaputra, D ;
Li, SD .
MEDICAL PHYSICS, 2005, 32 (01) :65-75
[10]  
Ebe K, 2004, INT J RADIAT ONCOL, V60, pS604