Sodium hydrogen sulfate as effective and reusable heterogeneous catalyst for the one-pot preparation of amidoalkyl naphthols

被引：55

作者：

Shaterian, Hamid Reza ^{[1
]}

Yarahmadi, Hossein ^{[1
]}

机构：

[1] Univ Sistan & Baluchestan, Fac Sci, Dept Chem, POB 98135-674, Zahedan, Iran

来源：

ARKIVOC | 2008年

关键词：

sodium hydrogen sulphate; amidoalkyl naphthol; multi-component reaction; heterogeneous catalyst;

D O I：

10.3998/ark.5550190.0009.212

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthesis of amidoalkyl naphthols using sodium hydrogen sulfate as heterogeneous catalyst is described. The thermal solvent-free and microwave green procedures offer advantages such as shorter reaction times, simple work-up, excellent yield, recovery and reusability of catalyst. It is noteworthy that 1-amidomethyl-2-naphthols can be converted in to important 'drug like' 1-aminomethyl-2-naphthols derivatives by amide hydrolysis reaction.

引用

页码：105 / 114

页数：10

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