Severe sensorimotor neuropathy after intake of highest dosages of vitamin B6

被引：42

作者：

Gdynia, Hans-Juergen ^{[1
]}

Mueller, Timo ^{[1
]}

Sperfeld, Anne-Dorte ^{[1
]}

Kuehnlein, Peter ^{[1
]}

Otto, Markus ^{[1
]}

Kassubek, Jan ^{[1
]}

Ludolph, Albert C. ^{[1
]}

机构：

[1] Univ Ulm, Dept Neurol, D-89081 Ulm, Germany

来源：

NEUROMUSCULAR DISORDERS | 2008年 / 18卷 / 02期

关键词：

vitamin B6; pyridoxine; hypervitaminosis; polyneuropathy; self-medication;

D O I：

10.1016/j.nmd.2007.09.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We illustrate a white caucasian patient with a severe sensorimotor neuropathy due to vitamin B6 hypervitaminosis. The patient used the pendulum to calculate his daily metabolic demands and ingested 9.6 g pyridoxine/day. To our knowledge, this is the highest dosage of vitamin B6 administered to humans over prolonged periods of time ever reported in the medical literature. The unique aspect of this case is the muscle weakness and motor findings on electrophysiological testing in what is suggested by the literature to be a pure sensory neuronopathy. (C) 2007 Elsevier B.V. All rights reserved.

引用

页码：156 / 158

页数：3

共 8 条

[1] ACUTE SENSORY NEUROPATHY-NEURONOPATHY FROM PYRIDOXINE OVERDOSE [J].