PHARMACEUTICAL ANALYSIS AND STANDARDIZATION OF AFOBAZOLE IN SOLID DOSAGE FORM (TABLETS)

被引：0
|
作者：
Grushevskaya, L. N. [1 ]
Milkina, S. E. [2 ]
Stepanenko, O. B. [1 ]
Volkova, M. Yu. [1 ]
Pyatin, B. M. [1 ]
Avdyunina, N. I. [1 ]
Alekseev, K. V. [1 ]
Sizyakov, S. A. [1 ]
机构：
[1] Russian Acad Med Sci, Zakusov State Inst Pharmacol, Moscow, Russia
[2] Sci Ctr Expertise Med Prod, Fed Serv Russian Federat Supervis Sphere Publ Hlt, Moscow, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 09期
关键词：
afobazole; tablets; pharmaceutical analysis;
D O I：
10.1007/s11094-010-0507-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The investigation was aimed at developing procedures for the pharmaceutical analysis and standardization of the new domestic anxiolytic afobazole in solid dosage form (tablets). The main pharmacopoeial tests have been carried out and methods for the determination (TLC, HPLC), identification (TLC, UV spectrophotometry), and quantitative assay (UV spectrophotometry, HPLC) have been worked out. The test for uniformity of composition and the dissolution test were carried out with the aid of UV spectrophotometry.
引用
收藏
页码：517 / 520
页数：4
相关论文
共 50 条
  • [31] GC Method Validation for the Analysis of Menthol in Suppository Pharmaceutical Dosage Form
    Abualhasan, Murad N.
    Zaid, Abdel Naser
    Jaradat, Nidal
    Mousa, Ayman
    INTERNATIONAL JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 2017
  • [32] Recovery of Active Pharmaceutical Ingredients from Unused Solid Dosage-Form Drugs
    Pratama, Dhanang Edy
    Hsieh, Wen-Chen
    Elmaamoun, Ahmed
    Lee, Hung Lin
    Lee, Tu
    ACS OMEGA, 2020, 5 (45): : 29147 - 29157
  • [33] Gimantan tablets: Analysis and standardization
    Tsvetkova E.A.
    Volkova M.Yu.
    Stepanenko O.B.
    Kislyak N.A.
    Shcherbakova O.V.
    Avdyunina N.I.
    Pyatin B.M.
    Pharmaceutical Chemistry Journal, 2002, 36 (1) : 48 - 50
  • [34] Lubricants in Pharmaceutical Solid Dosage Forms
    Li, Jinjiang
    Wu, Yongmei
    LUBRICANTS, 2014, 2 (01): : 21 - 43
  • [35] TABLETS OF COATED ASPIRIN MICROSPHERULES - A NEW DOSAGE FORM
    GREEN, DM
    JOURNAL OF NEW DRUGS, 1966, 6 (05): : 294 - +
  • [36] Near infrared transmittance analysis for the assay of solid pharmaceutical dosage forms
    Corti, P
    Ceramelli, G
    Dreassi, E
    Mattii, S
    ANALYST, 1999, 124 (05) : 755 - 758
  • [37] Developing methods for analysis of the solid dosage form (capsules) of cardiocyclide
    M. S. Sergeeva
    L. N. Grushevskaya
    B. M. Pyatin
    K. V. Alekseev
    N. I. Avdyunina
    E. V. Blynskaya
    Pharmaceutical Chemistry Journal, 2010, 44 : 278 - 281
  • [38] DEVELOPING METHODS FOR ANALYSIS OF THE SOLID DOSAGE FORM (CAPSULES) OF CARDIOCYCLIDE
    Sergeeva, M. S.
    Grushevskaya, L. N.
    Pyatin, B. M.
    Alekseev, K. V.
    Avdyunina, N. I.
    Blynskaya, E. V.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2010, 44 (05) : 278 - 281
  • [39] Hydrotropic solubilization in spectrophotometric analysis of cefixime in solid dosage form
    Maheshwari, R. K.
    Dubey, Nidhi
    Dubey, Nitin
    Singh, Mahaveer
    ASIAN JOURNAL OF CHEMISTRY, 2008, 20 (01) : 375 - 379
  • [40] Formulation and Evaluation of Phanera variegata Linn. Mucilage as a Pharmaceutical Binder in Solid Dosage Form
    Bansal, Keshav
    Bajpai, Meenakshi
    INDIAN JOURNAL OF PHARMACEUTICAL EDUCATION AND RESEARCH, 2020, 54 (04) : 971 - 982
12345