PHARMACEUTICAL ANALYSIS AND STANDARDIZATION OF AFOBAZOLE IN SOLID DOSAGE FORM (TABLETS)

被引：0
|
作者：
Grushevskaya, L. N. [1 ]
Milkina, S. E. [2 ]
Stepanenko, O. B. [1 ]
Volkova, M. Yu. [1 ]
Pyatin, B. M. [1 ]
Avdyunina, N. I. [1 ]
Alekseev, K. V. [1 ]
Sizyakov, S. A. [1 ]
机构：
[1] Russian Acad Med Sci, Zakusov State Inst Pharmacol, Moscow, Russia
[2] Sci Ctr Expertise Med Prod, Fed Serv Russian Federat Supervis Sphere Publ Hlt, Moscow, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2010年 / 44卷 / 09期
关键词：
afobazole; tablets; pharmaceutical analysis;
D O I：
10.1007/s11094-010-0507-5
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The investigation was aimed at developing procedures for the pharmaceutical analysis and standardization of the new domestic anxiolytic afobazole in solid dosage form (tablets). The main pharmacopoeial tests have been carried out and methods for the determination (TLC, HPLC), identification (TLC, UV spectrophotometry), and quantitative assay (UV spectrophotometry, HPLC) have been worked out. The test for uniformity of composition and the dissolution test were carried out with the aid of UV spectrophotometry.
引用
收藏
页码：517 / 520
页数：4
相关论文
共 50 条
  • [1] Pharmaceutical analysis and standardization of afobazole in solid dosage form (tablets)
    L. N. Grushevskaya
    S. E. Milkina
    O. B. Stepanenko
    M. Yu. Volkova
    B. M. Pyatin
    N. I. Avdyunina
    K. V. Alekseev
    S. A. Sizyakov
    Pharmaceutical Chemistry Journal, 2010, 44 : 517 - 520
  • [2] Improvement of methodological approaches to the standardization of medicines in the pharmaceutical dosage form of tablets
    E. L. Kovaleva
    V. L. Bagirova
    L. I. Mitʼkina
    O. A. Matveeva
    E. R. Akopova
    N. A. Vinogradova
    Pharmaceutical Chemistry Journal, 2009, 43 : 668 - 676
  • [3] IMPROVEMENT OF METHODOLOGICAL APPROACHES TO THE STANDARDIZATION OF MEDICINES IN THE PHARMACEUTICAL DOSAGE FORM OF TABLETS
    Kovaleva, E. L.
    Bagirova, V. L.
    Mit'kina, L. I.
    Matveeva, O. A.
    Akopova, E. R.
    Vinogradova, N. A.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2009, 43 (12) : 668 - 676
  • [4] Pharmaceutical analysis and standardization of gimantan parenteral dosage form
    M. S. Sergeeva
    L. N. Grushevskaya
    B. M. Pyatin
    N. I. Avdyunina
    L. M. Gaevaya
    V. S. Klumova
    M. E. Dudenkova
    K. V. Alekseev
    E. A. Litvin
    Pharmaceutical Chemistry Journal, 2011, 45 : 499 - 502
  • [5] PHARMACEUTICAL ANALYSIS AND STANDARDIZATION OF GIMANTAN PARENTERAL DOSAGE FORM
    Sergeeva, M. S.
    Grushevskaya, L. N.
    Pyatin, B. M.
    Avdyunina, N. I.
    Gaevaya, L. M.
    Klumova, V. S.
    Dudenkova, M. E.
    Alekseev, K. V.
    Litvin, E. A.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2011, 45 (08) : 499 - 502
  • [6] PHARMACEUTICAL ANALYSIS AND STANDARDIZATION OF NOOPEPT TABLETS
    Grushevskaya, L. N.
    Avdyunina, N. I.
    Pyatin, B. M.
    Alekseev, K. V.
    Gaevaya, L. M.
    Sergeeva, M. S.
    Dudenkova, M. E.
    Klumova, V. S.
    Tikhonova, N. V.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2011, 45 (06) : 377 - 380
  • [7] Pharmaceutical analysis and standardization of noopept tablets
    L. N. Grushevskaya
    N. I. Avdyunina
    B. M. Pyatin
    K. V. Alekseev
    L. M. Gaevaya
    M. S. Sergeeva
    M. E. Dudenkova
    V. S. Klumova
    N. V. Tikhonova
    Pharmaceutical Chemistry Journal, 2011, 45 : 377 - 380
  • [8] Development of Formulation, Manufacturing Technology, and Standardization of Solid Pharmaceutical Dosage Form of Dilept, a Novel Atypical Neuroleptic
    Grushevskaya, L. N.
    Gusev, M., V
    Blynskaya, E., V
    Tikhonova, N., V
    Marachova, A., I
    Gaevaya, L. M.
    Avdyunina, N., I
    Alekseev, K., V
    Pyatin, B. M.
    Kondakov, S. E.
    MOSCOW UNIVERSITY CHEMISTRY BULLETIN, 2013, 68 (05) : 246 - 250
  • [9] Application of pressurized liquid extraction technology to pharmaceutical solid dosage form analysis
    Hoang, TH
    Farkas, R
    Wells, C
    McClintock, S
    Di Maso, M
    JOURNAL OF CHROMATOGRAPHY A, 2002, 968 (1-2) : 257 - 261
  • [10] Developing analytical techniques for GB-115 determination in solid dosage form (tablets)
    Klumova, V. S.
    Grushevskaya, L. N.
    Avdyunina, N. I.
    Pyatin, B. M.
    Gaevaya, L. M.
    Sergeeva, M. S.
    Dudenkova, M. E.
    Alekseev, K. V.
    Blynskaya, E. V.
    Tikhonova, N. V.
    Turchinskaya, K. G.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2012, 45 (12) : 736 - 740
12345