A novel method for the synthesis of pyrimido[1,2-a]benzimidazoles

被引：16

作者：

Vandyshev, Dmitriy Yu. ^{[1
]}

Shikhaliev, Khidmet S. ^{[1
]}

Kokonova, Anna V. ^{[1
]}

Potapov, Andrei Yu. ^{[1
]}

Kolpakova, Maria G. ^{[1
]}

Sabynin, Artem L. ^{[1
]}

Zubkov, Fedor I. ^{[2
]}

机构：

[1] Voronezh State Univ, 1 Univ Skaya Sq, Voronezh 394006, Russia

[2] Peoples Friendship Univ Russia, 6 Miklukho Maklaya St, Moscow 117198, Russia

来源：

CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2016年 / 52卷 / 07期

关键词：

N-arylitaconimides; 1,2-diaminobenzimidazole; methypyrrolidine-2,5-dione; pyrimido[1,2-a]benzimidazole; polynucleophiles; ITACONIC ACID; IMIDAZOPYRIMIDINES; DERIVATIVES; MALEIMIDES; INHIBITORS;

D O I：

10.1007/s10593-016-1914-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of 1,2-diaminobenzimidazole with N-arylitaconimides was studied. It was found that 2-(10-amino-N-aryl-2-oxo-2,3,4,10-tetrahydropyrimido[1,2-a]benzimidazol-3-yl)acetamides were formed in the course of this reaction upon brief heating to reflux of the reagent mixture in 2-propanol in the presence of catalytic amounts of acetic acid.

引用

页码：493 / 497

页数：5

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